ArticleMolecules (Basel, Switzerland)2016
Biological Activities of the Essential Oil from Erigeron floribundus.
Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Antifungal Potential of Essential Oils From Native Mexican Species: Chemical Composition and In Vitro Vapor-Phase Analyses.Chemistry & biodiversity · 2026Article
- Clinical Potential of Essential Oils: Cytotoxicity, Selectivity Index, and Efficacy for Combating Gram-Positive ESKAPE Pathogens.Molecules (Basel, Switzerland) · 2025Review
- Greens in the Gaps: Diversity and the Ecological Potential of Urban Spontaneous Vegetation in Sidewalk Ecosystems.Plants (Basel, Switzerland) · 2025Article
- Compositional Variability of Essential Oils and Their Bioactivity in Native and InvasiveMolecules (Basel, Switzerland) · 2025Review
- Antidiabetic activity of the aqueous extract ofMetabolism open · 2024Article
- Optimization of Supercritical Carbon Dioxide Extraction ofAntioxidants (Basel, Switzerland) · 2022Article
- Zinc(II) Complex with Pyrazolone-Based Hydrazones is Strongly Effective againstInorganic chemistry · 2022Article
- Antitrypanosomal Activity ofAntibiotics (Basel, Switzerland) · 2021Article
- The Chemical Compositions of Essential Oils Derived fromMolecules (Basel, Switzerland) · 2020Article
- Trypanocidal Essential Oils: A Review.Molecules (Basel, Switzerland) · 2020Review
- Phytochemical Analysis and Trypanocidal Activity ofMolecules (Basel, Switzerland) · 2020Article
- Identification ofACS omega · 2019Article
- Evaluation of the Anti-Trypanosomal Activity of Vietnamese Essential Oils, with Emphasis onMolecules (Basel, Switzerland) · 2019Article
- Active Essential Oils and Their Components in Use against Neglected Diseases and Arboviruses.Oxidative medicine and cellular longevity · 2019Review
- Chemical composition and evaluation of the antibacterial and Cytotoxic activities of the essential oil from the leaves of Myracrodruon urundeuva.BMC complementary and alternative medicine · 2017Article
- Trypanosoma brucei Inhibition by Essential Oils from Medicinal and Aromatic Plants Traditionally Used in Cameroon (Azadirachta indica, Aframomum melegueta, Aframomum daniellii, Clausena anisata, Dichrostachys cinerea and Echinops giganteus).International journal of environmental research and public health · 2017Article
- Chemical Composition, Antioxidant, Antimicrobial and Cytotoxic Activities of Essential Oil from Premna microphylla Turczaninow.Molecules (Basel, Switzerland) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Erigeron floribundus (Asteraceae) is an herbaceous plant widely used in Cameroonian traditional medicine to treat various diseases of microbial and non-microbial origin. In the present study, we evaluated the in vitro biological activities displayed by the essential oil obtained from the aerial parts of E. floribundus, namely the antioxidant, antimicrobial and antiproliferative activities. Moreover, we investigated the inhibitory effects of E. floribundus essential oil on nicotinate mononucleotide adenylyltransferase (NadD), a promising new target for developing novel antibiotics, and Trypanosoma brucei, the protozoan parasite responsible for Human African trypanosomiasis. The essential oil composition was dominated by spathulenol (12.2%), caryophyllene oxide (12.4%) and limonene (8.8%). The E. floribundus oil showed a good activity against Staphylococcus aureus (inhibition zone diameter, IZD of 14 mm, minimum inhibitory concentration, MIC of 512 µg/mL). Interestingly, it inhibited the NadD enzyme from S. aureus (IC50 of 98 µg/mL), with no effects on mammalian orthologue enzymes. In addition, T. brucei proliferation was inhibited with IC50 values of 33.5 µg/mL with the essential oil and 5.6 µg/mL with the active component limonene. The essential oil exhibited strong cytotoxicity on HCT 116 colon carcinoma cells with an IC50 value of 14.89 µg/mL, and remarkable ferric reducing antioxidant power (tocopherol-equivalent antioxidant capacity, TEAC = 411.9 μmol·TE/g).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.