ReviewMolecules (Basel, Switzerland)2016
Determination of the Absolute Configurations of Chiral Drugs Using Chiroptical Spectroscopy.
Review in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 47 citations in OpenAlex.
- Chiroptical Signature and Absolute Configuration of Tröger's Base-Based Triangular Macrocycles.ACS omega · 2025Article
- A green bio-organic catalyst (taurine) promoted one-pot synthesis of (RSC advances · 2024Article
- A Computational Protocol for Vibrational Circular Dichroism Spectra of Cyclic Oligopeptides.The journal of physical chemistry. A · 2022Article
- Tackling Stereochemistry in Drug Molecules with Vibrational Optical Activity.Pharmaceuticals (Basel, Switzerland) · 2021Review
- GUI Implementation of VCDtools, A Program to Analyze Computed Vibrational Circular Dichroism Spectra.Journal of chemical information and modeling · 2020Article
- Progressive Stereo Locking (PSL): A Residual Dipolar Coupling Based Force Field Method for Determining the Relative Configuration of Natural Products and Other Small Molecules.ACS chemical biology · 2017Article
- Recent Advances in Multinuclear NMR Spectroscopy for Chiral Recognition of Organic Compounds.Molecules (Basel, Switzerland) · 2017Review
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chiroptical spectroscopy has emerged as a promising tool for the determination of absolute configurations and predominant conformations of chiral molecules in academic laboratories. This promise has led to the adaption of chiroptical spectroscopic methods as valuable tools in chiral drug discovery research programs of the pharmaceutical industry. Most major pharmaceutical companies have invested in in-house chiroptical spectroscopy applications and reported successful outcomes. In the context of continuously increasing applications of chiroptical spectroscopy for chiral molecular structure determination, a review of recent developments and applications for chiral drugs is presented in this manuscript.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.