ArticleAJOB empirical bioethics
Concerns about Genetic Testing for Schizophrenia among Young Adults at Clinical High Risk for Psychosis.
Article in AJOB empirical bioethics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 20 citations in OpenAlex.
- Ethical and social issues in prediction of risk of severe mental illness: a scoping review and thematic analysis.BMC psychiatry · 2025Article
- Polygenic risk for schizophrenia and subjective well-being in a general population sample.Psychological medicine · 2025Article
- The Ethics of Risk Prediction for Psychosis and Suicide Attempt in Youth Mental Health.The Journal of pediatrics · 2023Review
- Perceptions of causal attribution and attitudes to genetic testing among people with schizophrenia and their first-degree relatives.European journal of human genetics : EJHG · 2022Article
- Data sharing in the age of predictive psychiatry: an adolescent perspective.Evidence-based mental health · 2022Article
- The benefit of foresight? An ethical evaluation of predictive testing for psychosis in clinical practice.NeuroImage. Clinical · 2020Article
- Anticipating the Ethical Challenges of Psychiatric Genetic Testing.Current psychiatry reports · 2017Review
- Hopes and Expectations Regarding Genetic Testing for Schizophrenia Among Young Adults at Clinical High-Risk for Psychosis.Journal of psychiatric practice · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundGenetic tests for schizophrenia may introduce risks and benefits. Among young adults at clinical high-risk for psychosis, little is known about their concerns and how they assess potential risks.
methodsWe conducted semi-structured interviews with 15 young adults at clinical high-risk for psychosis to ask about their concerns.
resultsParticipants expressed concerns about test reliability, data interpretation, stigma, psychological harm, family planning, and privacy. Participants' responses showed some departure from the ethics literature insofar as participants were primarily interested in reporting their results to people to whom they felt emotionally close, and expressed little consideration of biological closeness. Additionally, if tests showed an increased genetic risk for schizophrenia, four clinical high-risk persons felt obligated to tell an employer and another three would "maybe" tell an employer, even in the absence of clinical symptoms.
conclusionsThese findings suggest opportunities for clinicians and genetic counselors to intervene with education and support.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.