Evidence map›Paper›PMID 27529048›Full record

ArticleCase reports in rheumatology2016

Henoch-Schönlein Purpura with Adalimumab Therapy for Ulcerative Colitis: A Case Report and Review of the Literature.

Joseph J LaConti, Jean A Donet, Jeong Hee Cho-Vega, Daniel A Sussman, Dana Ascherman, Amar R Deshpande

Abstract read
In one paragraph

Article in Case reports in rheumatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Biologics for childhood systemic vasculitis.Pediatric nephrology (Berlin, Germany) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joseph J LaContiDivision of Rheumatology, University of Miami Leonard Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0002-5995-3768
Jean A DonetDivision of Gastroenterology, University of Miami Leonard Miller School of Medicine, Miami, FL 33136, USA.
Jeong Hee Cho-VegaDepartment of Pathology, University of Miami Leonard Miller School of Medicine, Miami, FL 33136, USA.
Daniel A SussmanDivision of Gastroenterology, University of Miami Leonard Miller School of Medicine, Miami, FL 33136, USA.
Dana AschermanDivision of Rheumatology, University of Miami Leonard Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0002-1387-0860
Amar R DeshpandeDivision of Gastroenterology, University of Miami Leonard Miller School of Medicine, Miami, FL 33136, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor necrosis factor-α (TNFα) inhibitor therapy has signified an important milestone in the fight against many rheumatological disorders and inflammatory bowel disease (IBD). Cutaneous adverse events caused by this class of medications are well known but relatively uncommon. Most reactions are mild and rarely warrant treatment withdrawal. Henoch-Schönlein purpura (HSP) is a disease with cutaneous vasculitis, arthritis, and gastrointestinal and renal involvement that is usually seen in children, though the worst complications are typically seen in adults. We present a case of HSP complicating adalimumab treatment in a patient with ulcerative colitis who had achieved endoscopic remission. We review similar cases reported in the literature and discuss the consequences of these autoimmune diseases.

Identifiers

PMID27529048
PMCPMC4978839

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.