Evidence map›Paper›PMID 27528758›Full record

ArticleBiochemical Society transactions2016

The quantum mitochondrion and optimal health.

Alistair V W Nunn, Geoffrey W Guy, Jimmy D Bell

Open access · hybridAbstract read
In one paragraph

Article in Biochemical Society transactions, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Quantum biology: From mechanisms to medicine.Clinical and translational medicine · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Non-chemical signalling between mitochondria.Frontiers in physiology · 2023
    Article
  12. The Fractal Viewpoint of Tumors and Nanoparticles.Current medicinal chemistry · 2023
    Review
  13. Review
  14. Review
  15. Ambient and supplemental magnetic fields promote myogenesisFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alistair V W NunnResearch Centre for Optimal Health, Department of Life Sciences, University of Westminster, London W1W 6UW, U.K. alistair.nunn@btconnect.com.
Geoffrey W GuyGW Pharmaceuticals, Porton Down, Salisbury, Wiltshire SP4 0JQ, U.K.
Jimmy D BellResearch Centre for Optimal Health, Department of Life Sciences, University of Westminster, London W1W 6UW, U.K.
University of Westminster · GBGW Pharmaceuticals (United Kingdom) · GB

Funding

Medical Research Council MC_U120061305
6 · The paper itself

Abstract

A sufficiently complex set of molecules, if subject to perturbation, will self-organize and show emergent behaviour. If such a system can take on information it will become subject to natural selection. This could explain how self-replicating molecules evolved into life and how intelligence arose. A pivotal step in this evolutionary process was of course the emergence of the eukaryote and the advent of the mitochondrion, which both enhanced energy production per cell and increased the ability to process, store and utilize information. Recent research suggest that from its inception life embraced quantum effects such as 'tunnelling' and 'coherence' while competition and stressful conditions provided a constant driver for natural selection. We believe that the biphasic adaptive response to stress described by hormesis-a process that captures information to enable adaptability, is central to this whole process. Critically, hormesis could improve mitochondrial quantum efficiency, improving the ATP/ROS ratio, whereas inflammation, which is tightly associated with the aging process, might do the opposite. This all suggests that to achieve optimal health and healthy aging, one has to sufficiently stress the system to ensure peak mitochondrial function, which itself could reflect selection of optimum efficiency at the quantum level.

Indexed as

Energy MetabolismHealth StatusLongevityAdaptation, PhysiologicalAdenosine TriphosphateAgingAnimalsBiological EvolutionHormesisHumansInflammationMitochondriaModels, BiologicalReactive Oxygen SpeciesAdenosine TriphosphateReactive Oxygen Speciesagingcognitionhormesisinflammationmitochondriaquantumthermodynamics

Identifiers

PMID27528758
PMCPMC5264502
OpenAlexW2508661753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.