Trial reportThe British journal of general practice : the journal of the Royal College of General Practitioners2016
Targeted case finding in the prevention of cardiovascular disease: a stepped wedge cluster randomised controlled trial.
Trial report in The British journal of general practice : the journal of the Royal College of General Practitioners, 2016. The graph read 2 numbers from its abstract, feeding 2 cells of the map: it . Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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Assessment of lipid levels increased significantly, at 26.4% (99% CI = 5.3 to 47.5, P = 0.001) CONCLUSION: Targeted case finding programmes can increase the number of high-risk patients started on antihypertensive and statin treatment.
Read, but not usablea number the graph found but could not read as for or against
After adjustment for clustering and temporal effects the risk difference was 15.5% (95% CI = 3.9 to 27.1, P = 0.009).
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Digital & care-delivery×lipids
No readable resultOpen on the map →What to test next →2 readable studies in this cell: 0 favour the treatment, 1 find no difference, 1 favour the comparator.
Digital & care-delivery×blood pressure
No readable resultOpen on the map →What to test next →1 readable study in this cell: 0 favour the treatment, 1 find no difference, 0 favour the comparator.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Pooled it
- Trial
- Improving case-finding of long-term health problems in disadvantaged communities: A Policy-focused Evidence Brief.Public health in practice (Oxford, England) · 2026Article
- Article
- NHS Health Checks: an observational study of equity and outcomes 2009-2017.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Observational
- GP incentives to design hypertension and atrial fibrillation local quality-improvement schemes: a controlled before-after study in UK primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019Article
- Article
- Reporting of stepped wedge cluster randomised trials: extension of the CONSORT 2010 statement with explanation and elaboration.BMJ (Clinical research ed.) · 2018Article
- NHS health checks: a cross- sectional observational study on equity of uptake and outcomes.BMC health services research · 2018Observational
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The marked sentences are the ones the graph read a number from.
backgroundIndividuals at high risk of cardiovascular disease (CVD) are undertreated.
aimTo evaluate the effectiveness of a programme of targeted, nurse-led case finding for CVD prevention in primary care. DESIGN AND
settingTargeted case finding for CVD prevention was implemented in urban West Midlands general practices between February 2009 and August 2012, and evaluated as a stepped wedge cluster randomised trial.
methodUntreated patients aged 35-74 years and at ≥20% 10-year CVD risk were identified, invited for assessment by a project nurse, and referred to their GP for treatment initiation. The primary outcome was the proportion of high-risk patients prescribed antihypertensives or statins after exposure to the intervention compared with an equivalent period of time prior to exposure. Secondary outcomes included assessment of CVD risk factors.
resultsIn 26 sequentially randomised general practices the exposed group consisted of 2926 untreated high-risk patients identified at the start of the intervention, with 2969 patients identified at the start of the unexposed period. The trial was well balanced in terms of age, sex, and cardiovascular risk factors. In the exposed period 19.7% of patients were prescribed antihypertensives or statins, and 10.8% of patients in the unexposed period. After adjustment for clustering and temporal effects the risk difference was 15.5% (95% CI = 3.9 to 27.1, P = 0.009). Assessment of lipid levels increased significantly, at 26.4% (99% CI = 5.3 to 47.5, P = 0.001)
conclusionTargeted case finding programmes can increase the number of high-risk patients started on antihypertensive and statin treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.