Evidence map›Paper›PMID 27528655›Full record

ReviewThe Journal of cell biology2016

Toll-tally tubular: A newly identified Toll-like receptor-FoxO pathway regulates dynamics of the neuronal microtubule network.

Kate O'Connor-Giles

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. KIF2A decreases IL-33 production and attenuates allergic asthmatic inflammation.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Kate O'Connor-GilesLaboratory of Genetics, University of Wisconsin-Madison, Madison, WI 53706 oconnorgiles@wisc.edu.
University of Wisconsin–Madison · US

Funding

Molecular mechanisms of synapse assembly and functionR01NS078179 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI O'CONNOR-GILES, KATHALEEN M · 2013 to 2023
$3.6M
CRISPR/Cas9 tools for identifying and manipulating diverse neuronal populationsR21NS088830 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI O'CONNOR-GILES, KATHALEEN M · 2014 to 2015
$406k
NINDS NIH HHS R01 NS078179NINDS NIH HHS R21 NS088830
6 · The paper itself

Abstract

Recent studies reveal a conserved role for FoxO transcription factors in establishing neuronal structure and circuit function. In this issue, McLaughlin et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201601014) identify a novel Toll-like receptor-FoxO pathway that represses the mitotic kinesin Pavarotti/MKLP1 to promote dynamic microtubules required for axonal transport and activity-dependent remodeling of presynaptic terminals.

Indexed as

Signal TransductionAnimalsForkhead Transcription FactorsHumansMicrotubulesModels, BiologicalNeuronsToll-Like ReceptorsForkhead Transcription FactorsToll-Like Receptors

Identifiers

PMID27528655
PMCPMC4987299
OpenAlexW2516034981

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.