ArticleJournal of magnetic resonance imaging : JMRI2017
Diagnostic accuracy of intracellular uptake rates calculated using dynamic Gd-EOB-DTPA-enhanced MRI for hepatic fibrosis stage.
Article in Journal of magnetic resonance imaging : JMRI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03025074 (Virology, Immunology and Mechanisms of Liver Disease in Patients With Hepatitis C and Other Liver Diseases), which is not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Virology, Immunology and Mechanisms of Liver Disease in Patients With Hepatitis C and Other Liver Diseases
Who cites it
14 citing papers in PubMed.
- Pharmacokinetic modelling of MRI-based liver function for risk assessment in primary sclerosing cholangitis: a prospective pilot study.European radiology experimental · 2026Article
- Go Fish! Hepatic Uptake of Clinical Hepatospecific Gadolinium-Based MRI Contrast Agents in Zebrafish is Similar to Humans.Molecular imaging and biology · 2025Article
- Species-Specific Hepatic Uptake of [Molecular imaging and biology · 2025Article
- Article
- Simultaneous evaluation of perfusion and morphology using GRASP MRI in hepatic fibrosis.European radiology · 2022Article
- Dynamic contrast-enhanced MRI perfusion quantification in hepatocellular carcinoma: comparison of gadoxetate disodium and gadobenate dimeglumine.European radiology · 2021Article
- Magnetic resonance-based biomarkers in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.Endocrinology, diabetes & metabolism · 2020Review
- Article
- Model-inferred mechanisms of liver function from magnetic resonance imaging data: Validation and variation across a clinically relevant cohort.PLoS computational biology · 2019Article
- Combined morphological and functional liver MRI using spin-lattice relaxation in the rotating frame (T1ρ) in conjunction with Gadoxetic Acid-enhanced MRI.Scientific reports · 2019Article
- Prospective comparison of diffusion-weighted MRI and dynamic Gd-EOB-DTPA-enhanced MRI for detection and staging of hepatic fibrosis in primary sclerosing cholangitis.European radiology · 2019Article
- Liver Fibrosis Conventional and Molecular Imaging Diagnosis Update.Journal of liver · 2019Article
- Quantitative assessment of hepatic fibrosis in chronic hepatitis B and C: T1 mapping on Gd-EOB-DTPA-enhanced liver magnetic resonance imaging.World journal of gastroenterology · 2018Observational
- Isolated Perfused Rat Livers to Quantify the Pharmacokinetics and Concentrations of Gd-BOPTA.Contrast media & molecular imaging · 2018Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
purposeTo assess the diagnostic accuracy of intracellular uptake rates (K MATERIALS AND
methodsThis was a case-control study design. Dynamic Gd-EOB-DTPA-enhanced 1.5T magnetic resonance imaging (MRI) was performed prospectively in 22 subjects with varying known stages of hepatic fibrosis. PK parameters and CEI were derived from the whole livers and from three fixed regions of interest (ROIs) in all subjects. Spearman rank correlation coefficients were computed to assess the relationship between fibrosis stages and each parameter. Receiver operating characteristic (ROC) curves were constructed to discriminate severe fibrosis (stages 3-4) from nonsevere fibrosis (stages 0-2). The coefficient of variation (CV) was calculated to assess variability in parameters between ROIs.
resultsK
conclusionHepatocyte intracellular uptake rate, K LEVEL OF EVIDENCE: 2 J. Magn. Reson. Imaging 2017;45:1177-1185.
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