Evidence map›Paper›PMID 27527670›Full record

Trial reportContraception2017

Effect of BMI and body weight on pregnancy rates with LNG as emergency contraception: analysis of four WHO HRP studies.

Mario Philip R Festin, Alexandre Peregoudov, Armando Seuc, James Kiarie, Marleen Temmerman

Open access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Contraception, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 50 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Photovoice as a Methodology in Obesity Research: A Scoping Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Article
  4. Review
  5. Review
  6. Non-Hormonal Contraception.Journal of clinical medicine · 2023
    Review
  7. Article
  8. Article
  9. Observational
  10. State of emergency contraception in the U.S., 2018.Contraception and reproductive medicine · 2018
    Review
  11. Piroxicam Plus Plan B for Emergency Contraception.Journal of the American Board of Family Medicine : JABFM
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 5 countries.

Mario Philip R FestinDepartment of Reproductive Health and Research, UNDP - UNFPA- UNICEF - WHO - World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), World Health Organization. Electronic address: festinma@who.int.
Alexandre PeregoudovDepartment of Reproductive Health and Research, UNDP - UNFPA- UNICEF - WHO - World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), World Health Organization. Electronic address: sasha.np@gmail.com.
Armando SeucDepartment of Reproductive Health and Research, UNDP - UNFPA- UNICEF - WHO - World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), World Health Organization. Electronic address: armandoseuc@infomed.sld.cu.
James KiarieDepartment of Reproductive Health and Research, UNDP - UNFPA- UNICEF - WHO - World Bank Special Programme of Research, Development and Research Training in Human Reproduction (HRP), World Health Organization. Electronic address: kiariej@who.int.
Marleen TemmermanAga Khan University Center for Women's Health and Research. Electronic address: marleen.temmerman@aku.edu.
World Health Organization · CHAga Khan University · PK

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectiveTo estimate the effect of increased body weight and body mass index (BMI) on pregnancy rates with levonorgestrel (LNG) 1.5mg used as emergency contraception (EC).

methodsThe study reviewed data from 6873 women in four WHO-HRP randomized trials on EC conducted between 1993 and 2010. Participants took either 1.5mg of LNG as a single dose or in two doses 12h apart, up to 120h of unprotected intercourse. Contraceptive efficacy (pregnancy rates) at different weight and BMI categories was evaluated.

resultsOverall pregnancy rate was low at 1.2%. Pregnancy rates were also low in women weighing over 80kg (0.7%) and who were obese (BMI over 30kg/m

conclusionsPregnancy rates with use of LNG 1.5mg for EC were low at less than 3% across different weight and BMI categories. Pooled analyses showed an increase in pregnancy rates among obese women (BMI more than 30kg/m IMPLICATIONS: Access to LNG as EC should still be promoted to women who need them, and not be restricted in any weight or BMI category, with additional attention for counselling and advice for obese women.

Indexed as

Body Mass IndexPregnancy RateAdultContraception, PostcoitalContraceptives, Oral, SyntheticFemaleHumansLevonorgestrelLogistic ModelsObesityPregnancyRisk AssessmentYoung AdultContraceptives, Oral, SyntheticLevonorgestrelBody mass index (BMI)Body weightEmergency contraceptionHormonal contraceptionLevonorgestrel

Identifiers

PMID27527670
PMCPMC5357708
OpenAlexW2517903636

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.