Evidence map›Paper›PMID 27527665›Full record

ReviewAdvanced drug delivery reviews2017

Placental control of drug delivery.

Sanaalarab Al-Enazy, Shariq Ali, Norah Albekairi, Marwa El-Tawil, Erik Rytting

Abstract readReview
In one paragraph

Review in Advanced drug delivery reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 112 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Sanaalarab Al-EnazyDepartment of Pharmacology & Toxicology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Shariq AliDepartment of Pharmacology & Toxicology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Norah AlbekairiDepartment of Pharmacology & Toxicology, King Saud University, Riyadh, Saudi Arabia.
Marwa El-TawilDepartment of Pharmacology, Tanta University, Tanta, Egypt.
Erik RyttingDepartment of Obstetrics & Gynecology, University of Texas Medical Branch, Galveston, TX 77555, USA. Electronic address: erik.rytting@utmb.edu.
The University of Texas Medical Branch at Galveston · USKing Saud University · SATanta University · EG

Funding

UTMB OPRC Administrative CoreU54HD047891 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI DUKES, KIMBERLY A. · 2015 to 2019
$4.8M
Pharmacokinetic and pharmacogenomic approach to indomethacin therapy in pregnancyR01HD083003 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI RYTTING, ERIK · 2015 to 2018
$1.5M
NICHD NIH HHS R01 HD083003NICHD NIH HHS U54 HD047891
6 · The paper itself

Abstract

The placenta serves as the interface between the maternal and fetal circulations and regulates the transfer of oxygen, nutrients, and waste products. When exogenous substances are present in the maternal bloodstream-whether from environmental contact, occupational exposure, medication, or drug abuse-the extent to which this exposure affects the fetus is determined by transport and biotransformation processes in the placental barrier. Advances in drug delivery strategies are expected to improve the treatment of maternal and fetal diseases encountered during pregnancy.

Indexed as

Maternal-Fetal ExchangePlacentaDrug Delivery SystemsFemaleHumansOxygenPharmaceutical PreparationsPregnancyOxygenPharmaceutical PreparationsBiotransformationPlacentaPregnancyTransporters

Identifiers

PMID27527665
PMCPMC5303687
OpenAlexW2517000680

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.