ArticleAngewandte Chemie (International ed. in English)2016
DNA Origami Rotaxanes: Tailored Synthesis and Controlled Structure Switching.
Article in Angewandte Chemie (International ed. in English), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Multi-Reconfigurable DNA Origami Nanolattice Driven by the Combination of Orthogonal Signals.JACS Au · 2023Article
- Design, Mechanical Properties, and Dynamics of Synthetic DNA Filaments.Bioconjugate chemistry · 2023Review
- Energy landscapes of rotary DNA origami devices determined by fluorescence particle tracking.Biophysical journal · 2022Article
- DNA-Based Molecular Machines.JACS Au · 2022Review
- Mechanical deformation behaviors and structural properties of ligated DNA crystals.Biophysical journal · 2022Article
- Conformational Control of DNA Origami by DNA Oligomers, Intercalators and UV Light.Methods and protocols · 2021Article
- DNA Origami Post-Processing by CRISPR-Cas12a.Angewandte Chemie (International ed. in English) · 2020Article
- Design, assembly, characterization, and operation of double-stranded interlocked DNA nanostructures.Nature protocols · 2019Article
- Reversible Covalent Stabilization of Stacking Contacts in DNA Assemblies.Angewandte Chemie (International ed. in English) · 2019Article
- Structural optimization of pseudorotaxane-forming oligonucleotides for efficient and stable complex formation.Nucleic acids research · 2018Article
- DNA Nanotechnology for Cancer Diagnosis and Therapy.International journal of molecular sciences · 2018Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Mechanically interlocked supramolecular assemblies are appealing building blocks for creating functional nanodevices. Herein, we describe the multistep assembly of large DNA origami rotaxanes that are capable of programmable structural switching. We validated the topology and structural integrity of these rotaxanes by analyzing the intermediate and final products of various assembly routes by electrophoresis and electron microscopy. We further analyzed two structure-switching behaviors of our rotaxanes, which are both mediated by DNA hybridization. In the first mechanism, the translational motion of the macrocycle can be triggered or halted at either terminus. In the second mechanism, the macrocycle can be elongated after completion of the rotaxane assembly, giving rise to a unique structure that is otherwise difficult to access.
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Registered trials
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