Evidence map›Paper›PMID 27527500›Full record

ReviewJournal of magnetic resonance imaging : JMRI2017

Restriction spectrum imaging: An evolving imaging biomarker in prostate MRI.

Ryan L Brunsing, Natalie M Schenker-Ahmed, Nathan S White, J Kellogg Parsons, Christopher Kane, Joshua Kuperman, Hauke Bartsch, Andrew Karim Kader, Rebecca Rakow-Penner, Tyler M Seibert and 9 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of magnetic resonance imaging : JMRI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ryan L BrunsingDepartment of Radiology, University of California San Diego, San Diego, California, USA.
Natalie M Schenker-AhmedDepartment of Radiology, University of California San Diego, San Diego, California, USA.
Nathan S WhiteDepartment of Radiology, University of California San Diego, San Diego, California, USA.
J Kellogg ParsonsDepartment of Surgery, University of California San Diego, San Diego, California, USA.
Christopher KaneDepartment of Surgery, University of California San Diego, San Diego, California, USA.
Joshua KupermanDepartment of Radiology, University of California San Diego, San Diego, California, USA.
Hauke BartschDepartment of Radiology, University of California San Diego, San Diego, California, USA.
Andrew Karim KaderDepartment of Surgery, University of California San Diego, San Diego, California, USA.
Rebecca Rakow-PennerDepartment of Radiology, University of California San Diego, San Diego, California, USA.
Tyler M SeibertDepartment of Radiation Medicine, University of California San Diego, San Diego, California, USA.
Daniel MargolisDepartment of Radiology, University of California Los Angeles, Los Angeles, California, USA.
Steven S RamanDepartment of Radiology, University of California Los Angeles, Los Angeles, California, USA.
Carrie R McDonaldDepartment of Psychiatry, University of California San Diego, La Jolla, California, USA.
Nikdokht FaridDepartment of Radiology, University of California San Diego, San Diego, California, USA.
Santosh KesariDepartment of Translational Neuro-Oncology and Neurotherapeutics, Pacific Neuroscience Institute and John Wayne Cancer Institute at Providence Saint John's Health Center, Los Angeles, California, USA.
Donna HanselDepartment of Pathology, University of California San Diego, San Diego, California, USA.
Ahmed ShabaikDepartment of Pathology, University of California San Diego, San Diego, California, USA.
Anders M DaleDepartment of Radiology, University of California San Diego, San Diego, California, USA.
David S KarowDepartment of Radiology, University of California San Diego, San Diego, California, USA.

Funding

U of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0M
Traning Clinical Scientists in Radiological ImagingT32EB005970 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Eric Y Chang, Rebecca Ann Rakow-Penner · 2007 to 2026
$3.2M
NIBIB NIH HHS T32 EB005970NINDS NIH HHS P30 NS047101
6 · The paper itself

Abstract

Restriction spectrum imaging (RSI) is a novel diffusion-weighted MRI technique that uses the mathematically distinct behavior of water diffusion in separable microscopic tissue compartments to highlight key aspects of the tissue microarchitecture with high conspicuity. RSI can be acquired in less than 5 min on modern scanners using a surface coil. Multiple field gradients and high b-values in combination with postprocessing techniques allow the simultaneous resolution of length-scale and geometric information, as well as compartmental and nuclear volume fraction filtering. RSI also uses a distortion correction technique and can thus be fused to high resolution T2-weighted images for detailed localization, which improves delineation of disease extension into critical anatomic structures. In this review, we discuss the acquisition, postprocessing, and interpretation of RSI for prostate MRI. We also summarize existing data demonstrating the applicability of RSI for prostate cancer detection, in vivo characterization, localization, and targeting. LEVEL OF EVIDENCE: 5 J. Magn. Reson. Imaging 2017;45:323-336.

Indexed as

Body WaterDiffusion Magnetic Resonance ImagingEvidence-Based MedicineHumansImage EnhancementImage Interpretation, Computer-AssistedMaleProstatic NeoplasmsReproducibility of ResultsSensitivity and SpecificitySignal Processing, Computer-Assistedbiomarkerdiffusion-weighted imagingprostate cancerrestriction spectrum imaging

Identifiers

PMID27527500
PMCPMC5222783

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.