Evidence map›Paper›PMID 27527496›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2016

Rubus imperialis (Rosaceae) extract and pure compound niga-ichigoside F1: wound healing and anti-inflammatory effects.

Talita Dacroce Tonin, Liliani Carolini Thiesen, Maria Luisa de Oliveira Nunes, Milena Fronza Broering, Marcos Paulo Donato, Marina Jagielski Goss, Marcel Petreanu, Rivaldo Niero, Isabel Daufenback Machado, José Roberto Santin

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Biological Effects ofPlants (Basel, Switzerland) · 2025
    Review
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  5. Review
  6. Review
  7. The Anti-Inflammatory Potential of an Ethanolic Extract fromInternational journal of molecular sciences · 2024
    Article
  8. The Antioxidant and Immunomodulatory Potential ofInternational journal of molecular sciences · 2023
    Article
  9. Article
  10. Review
  11. Review
  12. TanP: A Multifunctional Anionic Peptide FromFrontiers in molecular biosciences · 2021
    Article
  13. Article
  14. Review
  15. Effect ofOncoTargets and therapy · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Talita Dacroce ToninPrograma de Pós-Graduação em Ciências Farmacêuticas and Núcleo de Investigações Químico-Farmacêuticas-NIQFAR, Universidade do Vale do Itajaí - UNIVALI, Rua Uruguai, 458, Itajaí, SC, 88302-901, Brazil.
Liliani Carolini ThiesenPrograma de Pós-Graduação em Ciências Farmacêuticas and Núcleo de Investigações Químico-Farmacêuticas-NIQFAR, Universidade do Vale do Itajaí - UNIVALI, Rua Uruguai, 458, Itajaí, SC, 88302-901, Brazil.
Maria Luisa de Oliveira NunesPrograma de Pós-Graduação em Ciências Farmacêuticas and Núcleo de Investigações Químico-Farmacêuticas-NIQFAR, Universidade do Vale do Itajaí - UNIVALI, Rua Uruguai, 458, Itajaí, SC, 88302-901, Brazil.
Milena Fronza BroeringPrograma de Pós-Graduação em Ciências Farmacêuticas and Núcleo de Investigações Químico-Farmacêuticas-NIQFAR, Universidade do Vale do Itajaí - UNIVALI, Rua Uruguai, 458, Itajaí, SC, 88302-901, Brazil.
Marcos Paulo DonatoPrograma de Pós-Graduação em Ciências Farmacêuticas and Núcleo de Investigações Químico-Farmacêuticas-NIQFAR, Universidade do Vale do Itajaí - UNIVALI, Rua Uruguai, 458, Itajaí, SC, 88302-901, Brazil.
Marina Jagielski GossPrograma de Pós-Graduação em Ciências Farmacêuticas and Núcleo de Investigações Químico-Farmacêuticas-NIQFAR, Universidade do Vale do Itajaí - UNIVALI, Rua Uruguai, 458, Itajaí, SC, 88302-901, Brazil.
Marcel PetreanuPrograma de Pós-Graduação em Ciências Farmacêuticas and Núcleo de Investigações Químico-Farmacêuticas-NIQFAR, Universidade do Vale do Itajaí - UNIVALI, Rua Uruguai, 458, Itajaí, SC, 88302-901, Brazil.
Rivaldo NieroPrograma de Pós-Graduação em Ciências Farmacêuticas and Núcleo de Investigações Químico-Farmacêuticas-NIQFAR, Universidade do Vale do Itajaí - UNIVALI, Rua Uruguai, 458, Itajaí, SC, 88302-901, Brazil.
Isabel Daufenback MachadoPrograma de Pós-Graduação em Ciências Farmacêuticas and Núcleo de Investigações Químico-Farmacêuticas-NIQFAR, Universidade do Vale do Itajaí - UNIVALI, Rua Uruguai, 458, Itajaí, SC, 88302-901, Brazil.
José Roberto SantinPrograma de Pós-Graduação em Ciências Farmacêuticas and Núcleo de Investigações Químico-Farmacêuticas-NIQFAR, Universidade do Vale do Itajaí - UNIVALI, Rua Uruguai, 458, Itajaí, SC, 88302-901, Brazil. jrs.santin@univali.br.
Universidade do Vale do Itajaí · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we evaluate the anti-inflammatory and wound-healing effects of methanolic crude extract obtained from aerial parts (leaves and branches) of Rubus imperialis Chum. Schl. (Rosaceae) and the pure compound niga-ichigoside F1. Anti-inflammatory activity was determined in vivo and in vitro, and the healing effect was evaluated in surgical lesions in mice skin. The 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) assay and H

Indexed as

RubusAnimalsAnti-Inflammatory AgentsAntioxidantsBiphenyl CompoundsCarrageenanCell LineChemotaxis, LeukocyteDisease Models, AnimalDose-Response Relationship, DrugHydrogen PeroxideInflammationLipopolysaccharidesMacrophages, PeritonealMaleMethanol1,1-diphenyl-2-picrylhydrazylAnti-Inflammatory AgentsAntioxidantsBiphenyl CompoundsCarrageenanHydrogen PeroxideLipopolysaccharidesMethanolniga-ichigoside F1PicratesPlant ExtractsSaponinsSolventsFibroblastInflammationMacrophageWound healing

Identifiers

PMID27527496
OpenAlexW2517241815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.