ReviewBiosensors2016
Microfluidic Devices for Forensic DNA Analysis: A Review.
Review in Biosensors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review on Commercially Available Integrated Systems for Forensic DNA Analysis.Sensors (Basel, Switzerland) · 2023Pooled it
- Forensic Microbiomics and Trace Microbial Evidence: Molecular Innovations for Linking Suspects, Objects, and Environments.Microorganisms · 2026Review
- Review
- Modeling Alzheimer's disease with brain organoids: mechanisms, applications, and future directions.Frontiers in cell and developmental biology · 2026Review
- Recombinase polymerase amplification of forensic short tandem repeat loci.Scientific reports · 2025Article
- High-Density Microfluidic Chip with Vertical Structure for Digital PCR.Sensors (Basel, Switzerland) · 2025Article
- Investigations of the Laser Ablation Mechanism of PMMA Microchannels Using Single-Pass and Multi-Pass Laser Scans.Polymers · 2024Article
- Tailored micromixing in chemically patterned microchannels undergoing electromagnetohydrodynamic flow.Biomicrofluidics · 2024Article
- Advances in Microfluidic Systems and Numerical Modeling in Biomedical Applications: A Review.Micromachines · 2024Review
- Development of recombinase polymerase amplification-based colorimetric detection assay for rapid identification of invasive cassava mealybug,Saudi journal of biological sciences · 2024Article
- Direct and indirect technical guide for the early detection and management of fungal plant diseases.Current research in microbial sciences · 2024Review
- Advancing biological investigations using portable sensors for detection of sensitive samples.Heliyon · 2023Review
- On the Application of Microfluidic-Based Technologies in Forensics: A Review.Sensors (Basel, Switzerland) · 2023Review
- Recent Advances in Microfluidics-Based Electrochemical Sensors for Foodborne Pathogen Detection.Biosensors · 2023Review
- Nucleotide detection mechanism and comparison based on low-dimensional materials: A review.Frontiers in bioengineering and biotechnology · 2023Review
- 3D printing-enabled uniform temperature distributions in microfluidic devices.Lab on a chip · 2022Article
- Prebiotic Chemistry Experiments Using Microfluidic Devices.Life (Basel, Switzerland) · 2022Review
- Polymeric Microfluidic Devices Fabricated Using Epoxy Resin for Chemically Demanding and Day-Long Experiments.Biosensors · 2022Article
- A Digital Microfluidic RT-qPCR Platform for Multiple Detections of Respiratory Pathogens.Micromachines · 2022Article
- Ultra-rapid real-time microfluidic RT-PCR instrument for nucleic acid analysis.Lab on a chip · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microfluidic devices may offer various advantages for forensic DNA analysis, such as reduced risk of contamination, shorter analysis time and direct application at the crime scene. Microfluidic chip technology has already proven to be functional and effective within medical applications, such as for point-of-care use. In the forensic field, one may expect microfluidic technology to become particularly relevant for the analysis of biological traces containing human DNA. This would require a number of consecutive steps, including sample work up, DNA amplification and detection, as well as secure storage of the sample. This article provides an extensive overview of microfluidic devices for cell lysis, DNA extraction and purification, DNA amplification and detection and analysis techniques for DNA. Topics to be discussed are polymerase chain reaction (PCR) on-chip, digital PCR (dPCR), isothermal amplification on-chip, chip materials, integrated devices and commercially available techniques. A critical overview of the opportunities and challenges of the use of chips is discussed, and developments made in forensic DNA analysis over the past 10-20 years with microfluidic systems are described. Areas in which further research is needed are indicated in a future outlook.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.