ArticleBMC complementary and alternative medicine2016
Evaluation of the in vitro antibacterial activity of the solvent fractions of the leaves of Rhamnus prinoides L'Herit (Rhamnaceae) against pathogenic bacteria.
Article in BMC complementary and alternative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
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- Synthesis of 2-Ethylhexyl 5-Bromothiophene-2-Carboxylates; Antibacterial Activities againstMolecules (Basel, Switzerland) · 2024Article
- Endophytic Fungi Isolated fromPlants (Basel, Switzerland) · 2023Article
- Medicinal plants used for the management of respiratory diseases in Zimbabwe: Review and perspectives potential management of COVID-19.Physics and chemistry of the earth (2002) · 2022Article
- In vitro antibacterial and antifungal activities of extracts and fractions of leaves of Ricinus communis Linn against selected pathogens.Veterinary medicine and science · 2022Article
- Evaluation of the Antimicrobial Activity of Leaf Extracts ofJournal of experimental pharmacology · 2021Article
- Antioxidant and Antimicrobial Activity of Solvent Fractions ofJournal of experimental pharmacology · 2021Article
- Diversity, Chemical Constituents, and Biological Activities of Endophytic Fungi Isolated FromFrontiers in microbiology · 2021Article
- Evaluation of in-vivo antidiarrhoeal and in-vitro antibacterial activities of the root extract of Brucea antidysenterica J. F. Mill (Simaroubaceae).BMC complementary medicine and therapies · 2020Article
- Diversity, Chemical Constituents and Biological Activities of Endophytic Fungi Isolated fromMicroorganisms · 2020Article
- Antioxidant, Anti-inflammatory Activities and Polyphenol Profile of Rhamnus prinoides.Pharmaceuticals (Basel, Switzerland) · 2020Article
- In Vitro Antibacterial Activity of Selected Medicinal Plants in the Traditional Treatment of Skin and Wound Infections in Eastern Ethiopia.BioMed research international · 2018Article
- Antibacterial Activity ofSaudi journal of medicine & medical sciencesArticle
- Investigating In Vitro Antibacterial Activities of Medicinal Plants Having Folkloric Repute in Ethiopian Traditional Medicine.Journal of evidence-based integrative medicineArticle
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5 authors.
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Abstract
backgroundMedicinal plants play great roles in the treatment of various infectious diseases. Rhamnus prinoides is one of the medicinal plants used traditionally for treatment of bacterial diseases. The antibacterial activity of the crude extract of the plant had been shown by a previous study, but this study was undertaken to further the claimed medicinal use of the plant by screening its solvent fractions for the said activity so that it could serve as a basis for subsequent studies.
methodsThe solvent fractions of the plant were obtained by successive soxhlet extraction with solvents of increasing polarity, with chloroform and methanol, followed by maceration of the marc of methanol fraction with water. The antibacterial activity of the solvent fractions was evaluated on seven bacterial species using agar well diffusion method at different concentrations (78 mg/well, 39 mg/well and 19.5 mg/well) in the presence of positive and negative controls. The minimum inhibitory concentration of the solvent fractions was determined by micro-broth dilution method using resazurin as indicator.
resultMethanol and chloroform fractions revealed antibacterial activities against the growth of test bacterial strains with varying antibacterial spectrum and the susceptible bacterial species were Staphylococcus aureus, Streptococcus pyogen, Streptococcus pneumoniae and Salmonella typhi. The average minimum inhibitory concentration value of the methanol and chloroform fractions ranged from 8.13 mg/ml to 32.5 mg/ml and from 8.13 mg/ml to 16.25 mg/ml, respectively.
conclusionThe methanol and chloroform fractions demonstrated significant antibacterial activities against the growth of pathogenic bacteria but the aqueous fraction did not reveal antibacterial activity against any of the test bacteria.
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