ReviewCancer imaging : the official publication of the International Cancer Imaging Society2016
MRI of paediatric liver tumours: How we review and report.
Review in Cancer imaging : the official publication of the International Cancer Imaging Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Liver Transplantation in Malignancies: A Comprehensive and Systematic Review on Oncological Outcome.Visceral medicine · 2021Pooled it
- Fat-containing liver lesions expanding the magnetic resonance imaging signature of hepatoblastoma.Pediatric radiology · 2026Article
- 3D steady-state free precession in fetal body MR imaging: A useful adjunctive sequence.Acta radiologica open · 2026Article
- Current approach to diagnosis and treatment of focal nodular hyperplasia in children with a management algorithm.Clinical and experimental hepatology · 2025Review
- The changes in imaging following proton beam therapy for pediatric hepatoblastoma.European journal of pediatrics · 2025Article
- The Evaluation, Diagnosis, and Management of Infantile Hemangiomas-A Comprehensive Review.Journal of clinical medicine · 2025Review
- Congenital focal nodular hyperplasia-like lesion mimicking hepatoblastoma: anecdotal but plausible.World journal of pediatric surgery · 2025Article
- Accuracy of contrast-enhanced CT in liver neoplasms in children under 2 years age.Pediatric radiology · 2024Article
- Review on Pediatric Malignant Focal Liver Lesions with Imaging Evaluation: Part I.Diagnostics (Basel, Switzerland) · 2023Review
- Imaging of pediatric liver tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper.Pediatric blood & cancer · 2023Article
- Imaging of a glomus tumor of the liver in a child.Radiology case reports · 2020Article
- Liver Transplantation for Pediatric Liver Cancer.Cancers · 2020Review
- Contrast-enhanced ultrasound in the diagnosis of pediatric focal nodular hyperplasia and hepatic adenoma: interobserver reliability.Pediatric radiology · 2019Article
- Magnetic resonance imaging features of common focal liver lesions in children.Pediatric radiology · 2018Review
- Staging and following common pediatric malignancies: MRI versus CT versus functional imaging.Pediatric radiology · 2018Review
- [Imaging of abdominal tumors in childhood and adolescence : Part I: Background, hepatic, splenic and pancreatic tumors].Der Radiologe · 2018Article
- Fractures in children with newly diagnosed hepatoblastoma.Pediatric radiology · 2018Article
- Pedunculated focal nodular hyperplasia in a healthy toddler.Proceedings (Baylor University. Medical Center) · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Liver tumours are fortunately rare in children. Benign tumours such as haemangiomas and cystic mesenchymal hamartomas are typically seen in infancy, often before 6 months of age. After that age, malignant hepatic tumours increase in frequency. The differentiation of a malignant from benign lesion on imaging can often negate the need for biopsy. Ultrasound is currently the main screening tool for suspected liver pathology, and is ideally suited for evaluation of hepatic lesions in children due to their generally small size. With increasing research, public awareness and parental anxiety regarding radiation dosage from CT imaging, MRI is now unquestionably the modality of choice for further characterisation of hepatic mass lesions.Nevertheless the cost, length of imaging time and perceived complexity of a paediatric liver MR study can be intimidating to the general radiologist and referring clinician. This article outlines standard MR sequences utilised, reasons for their utilisation, types of mixed hepatocyte specific/extracellular contrast agents employed and imaging features that aid the interpretation of paediatric liver lesions. The two commonest paediatric liver malignancies, namely hepatoblastoma and hepatocellular carcinoma are described. Differentiation of primary hepatic malignancies with metastatic disease and mimickers of malignancy such as focal nodular hyperplasia (FNH) and hepatic adenomas are also featured in this review..Imaging should aim to clarify the presence of a lesion, the likelihood of malignancy and potential for complete surgical resection. Reviewing and reporting the studies should address these issues in a systematic fashion whilst also commenting upon background liver parenchymal appearances. Clinical information and adequate patient preparation prior to MR imaging studies help enhance the diagnostic yield.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.