Evidence map›Paper›PMID 27526937›Full record

ReviewCancer imaging : the official publication of the International Cancer Imaging Society2016

MRI of paediatric liver tumours: How we review and report.

Susan C Shelmerdine, Derek J Roebuck, Alexander J Towbin, Kieran McHugh

Open access · goldAbstract readReview
In one paragraph

Review in Cancer imaging : the official publication of the International Cancer Imaging Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  18. Pedunculated focal nodular hyperplasia in a healthy toddler.Proceedings (Baylor University. Medical Center) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Susan C ShelmerdineDepartment of Diagnostic Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK. susie.shelmerdine@gmail.com.
Derek J RoebuckDepartment of Interventional Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Alexander J TowbinDepartment of Pediatric Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Kieran McHughDepartment of Diagnostic Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Great Ormond Street Hospital for Children NHS Foundation Trust · GBCincinnati Children's Hospital Medical Center · US

Funding

Department of Health NIHR-CS-012-002
6 · The paper itself

Abstract

Liver tumours are fortunately rare in children. Benign tumours such as haemangiomas and cystic mesenchymal hamartomas are typically seen in infancy, often before 6 months of age. After that age, malignant hepatic tumours increase in frequency. The differentiation of a malignant from benign lesion on imaging can often negate the need for biopsy. Ultrasound is currently the main screening tool for suspected liver pathology, and is ideally suited for evaluation of hepatic lesions in children due to their generally small size. With increasing research, public awareness and parental anxiety regarding radiation dosage from CT imaging, MRI is now unquestionably the modality of choice for further characterisation of hepatic mass lesions.Nevertheless the cost, length of imaging time and perceived complexity of a paediatric liver MR study can be intimidating to the general radiologist and referring clinician. This article outlines standard MR sequences utilised, reasons for their utilisation, types of mixed hepatocyte specific/extracellular contrast agents employed and imaging features that aid the interpretation of paediatric liver lesions. The two commonest paediatric liver malignancies, namely hepatoblastoma and hepatocellular carcinoma are described. Differentiation of primary hepatic malignancies with metastatic disease and mimickers of malignancy such as focal nodular hyperplasia (FNH) and hepatic adenomas are also featured in this review..Imaging should aim to clarify the presence of a lesion, the likelihood of malignancy and potential for complete surgical resection. Reviewing and reporting the studies should address these issues in a systematic fashion whilst also commenting upon background liver parenchymal appearances. Clinical information and adequate patient preparation prior to MR imaging studies help enhance the diagnostic yield.

Indexed as

Carcinoma, HepatocellularChildHumansImage Interpretation, Computer-AssistedInfantLiver NeoplasmsMagnetic Resonance ImagingMedical RecordsUltrasonographyHepaticHepatobiliaryLesionLiverMalignancyMassMRIPaediatricTumour

Identifiers

PMID27526937
PMCPMC4986178
OpenAlexW2508509227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.