Evidence map›Paper›PMID 27526170›Full record

ArticleAdvances in experimental medicine and biology

Comparison of Two Algorithms for Analysis of Perfusion Computed Tomography Data for Evaluation of Cerebral Microcirculation in Chronic Subdural Hematoma.

Alexey O Trofimov, George Kalentiev, Oleg Voennov, Michail Yuriev, Darya Agarkova, Svetlana Trofimova, Denis E Bragin

Open access · greenAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Advances in experimental medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Alexey O TrofimovDepartment of Neurosurgery, Nizhniy Novgorod State Medical Academy, 10/1, Minin Str., Nizhniy Novgorod, 603950, Russia. xtro7@mail.ru.
George KalentievDepartment of Neurosurgery, Nizhniy Novgorod State Medical Academy, 10/1, Minin Str., Nizhniy Novgorod, 603950, Russia.
Oleg VoennovDepartment of Neurosurgery, Nizhniy Novgorod State Medical Academy, 10/1, Minin Str., Nizhniy Novgorod, 603950, Russia.
Michail YurievDepartment of Neurosurgery, Nizhniy Novgorod State Medical Academy, 10/1, Minin Str., Nizhniy Novgorod, 603950, Russia.
Darya AgarkovaDepartment of Neurosurgery, Nizhniy Novgorod State Medical Academy, 10/1, Minin Str., Nizhniy Novgorod, 603950, Russia.
Svetlana TrofimovaDepartment of Neurosurgery, Nizhniy Novgorod State Medical Academy, 10/1, Minin Str., Nizhniy Novgorod, 603950, Russia.
Denis E BraginDepartment of Neurosurgery, Nizhniy Novgorod State Medical Academy, 10/1, Minin Str., Nizhniy Novgorod, 603950, Russia.
Privolzhsky Research Medical University · RUUniversity of New Mexico · US

Funding

University of New Mexico (UNM) Center for Brain Recovery and RepairP20GM109089 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI MCKENZIE, SAMUEL ARNOLD · 2015 to 2024
$22.7M
Stroke Treatment by Modulation of Hemodynamics with Drag Reducing MoleculesR21NS091600 · NINDS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BRAGIN, DENIS E. · 2015 to 2016
$423k
NIGMS NIH HHS P20 GM109089NINDS NIH HHS R21 NS091600
6 · The paper itself

Abstract

The aim of this work was comparison of two algorithms of perfusion computed tomography (PCT) data analysis for evaluation of cerebral microcirculation in the perifocal zone of chronic subdural hematoma (CSDH). Twenty patients with CSDH after polytrauma were included in the study. The same PCT data were assessed quantitatively in cortical brain region beneath the CSDH (zone 1), and in the corresponding contralateral brain hemisphere (zone 2) without and with the use of perfusion calculation mode excluding vascular pixel 'Remote Vessels' (RV); 1st and 2nd analysis method, respectively. Comparison with normal values for perfusion indices in the zone 1 in the 1st analysis method showed a significant (p < 0.01) increase in CBV and CBF, and no significant increase in MTT and TTP. Use of the RV mode (2nd analysis method) showed no statistically reliable change of perfusion parameters in the microcirculatory blood flow of the 2nd zone. Maintenance of microcirculatory blood flow perfusion reflects the preservation of cerebral blood flow autoregulation in patients with CSDH.

Indexed as

AlgorithmsCerebrovascular CirculationMicrocirculationMultidetector Computed TomographyAdolescentAdultAgedAged, 80 and overChronic DiseaseFemaleHematoma, SubduralHomeostasisHumansImage Interpretation, Computer-AssistedMaleMiddle AgedCerebral microvasculatureChronic subdural hematomaPerfusion computerized tomographyPerifocal zone

Identifiers

PMID27526170
PMCPMC4988331
OpenAlexW2511184146

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.