Evidence map›Paper›PMID 27525745›Full record

ArticleWiener klinische Wochenschrift2016

Pulse contour cardiac output monitoring in acute heart failure patients : Assessment of hemodynamic measurements.

Bernhard Wernly, Michael Lichtenauer, Marcus Franz, Michael Fritzenwanger, Bjoern Kabisch, Hans-Reiner Figulla, Christian Jung

Open access · hybridAbstract read
In one paragraph

Article in Wiener klinische Wochenschrift, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Comparative Evaluation of Three Transthoracic Echocardiographic Techniques for Cardiac Output and Stroke Volume Assessment Across Hemodynamic States.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Bernhard WernlyUniversity Clinic of Internal Medicine II, Paracelsus Medical University, Salzburg, Austria.
Michael LichtenauerUniversity Clinic of Internal Medicine II, Paracelsus Medical University, Salzburg, Austria.
Marcus FranzClinic of Internal Medicine I, Friedrich-Schiller-University, Jena, Germany.
Michael FritzenwangerClinic of Internal Medicine I, Friedrich-Schiller-University, Jena, Germany.
Bjoern KabischClinic of Internal Medicine I, Friedrich-Schiller-University, Jena, Germany.
Hans-Reiner FigullaClinic of Internal Medicine I, Friedrich-Schiller-University, Jena, Germany.
Christian JungClinic of Cardiology, Pneumology and Angiology, University Clinic Duesseldorf, Moorenstr. 5, 40225, Duesseldorf, Germany. Christian.Jung@med.uni-duesseldorf.de.
Friedrich Schiller University Jena · DEParacelsus Medical University · ATDüsseldorf University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeart failure is known to be a major public health problem. Fluid redistribution contributes to acute heart failure; therefore, knowledge of hemodynamic parameters could be important for optimizing outcomes. The pulse contour cardiac output monitor PiCCO uses the single thermal indicator technique and pulse contour analysis to calculate hemodynamic parameters of preload, afterload, cardiac output, systemic vascular resistance and extravascular lung water.

objectivesWe primarily aimed to describe values and parameters seen in acute heart failure patients admitted to the intensive care unit (ICU) and secondly to investigate associations between hemodynamic measurements and survival data. MATERIAL AND

methodsIn this study 420 consecutive patients admitted to a tertiary medical university hospital ICU between January 2004 and December 2009 were retrospectively investigated. The study sample was divided into two subgroups: patients monitored by PiCCO (n = 47) and those not monitored by thermodilution measurements (n = 373). No predetermined treatment algorithm based on knowledge obtained by the PiCCO monitor was used and measurements were individually interpreted by the treating physician. The PiCCO monitor measurements were carried out according to manufacturer's directions.

resultsPatients with PiCCO monitoring were clinically in poorer health with a mean simplified acute physiology score II (SAPS2) of 45 ± 17 vs. 56 ± 20 (p < 0.01). The ICU mortality (22 % vs. 38 %, p = 0.02) and, at least as a tendency, long-term-mortality were increased in patients monitored by PiCCO (RR 1.49, 95 % CI 0.96-2.31, p = 0.08). We provide hemodynamic measurements in acute heart failure patients: cardiac index (2.7 ± 1.2 l/min/m²) was reduced, preload and extravascular lung water index (EVLWI, 11.5 ± 5.1 ml/kg body weight), representing lung edema, were increased.

conclusionWe provide real world values for PiCCO parameters in acutely decompensated heart failure. In our study patients who were clinically in poorer health were monitored with PiCCO, resulting in increased mortality in this group. Further prospective studies to investigate the effects of treatment decisions triggered by information obtained by PiCCO monitoring for patients in acute heart failure are needed.

Indexed as

Cardiac OutputExtravascular Lung WaterAgedBlood Pressure DeterminationDiagnosis, Computer-AssistedFemaleHeart FailureHumansMaleReproducibility of ResultsRespiratory Function TestsSensitivity and SpecificityThermodilutionVascular ResistanceCardiac indexCritically illHeart failureIntensive carePiCCO

Identifiers

PMID27525745
PMCPMC5161758
OpenAlexW2513447928

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.