ArticleJournal of the American Chemical Society2016
Syntheses of Denudatine Diterpenoid Alkaloids: Cochlearenine, N-Ethyl-1α-hydroxy-17-veratroyldictyzine, and Paniculamine.
Article in Journal of the American Chemical Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Divergent Total Synthesis of Denudatine Alkaloids Cochlearenine, Macrocentrine, Dictizine, 15-Veratroyl-17-Acetyl-19-Oxodictizine, and the Proposed Structure of Acochlearine.Angewandte Chemie (International ed. in English) · 2026Article
- Total Synthesis of Aconicarmisulfonine A, a Sulfonated Diterpene Alkaloid.Journal of the American Chemical Society · 2025Article
- A convergent fragment coupling strategy to access quaternary stereogenic centers.Chemical science · 2023Article
- An invocation for computational evaluation of isomerization transforms: cationic skeletal reorganizations as a case study.Natural product reports · 2021Review
- Total Synthesis of the Diterpenoid Alkaloid Arcutinidine Using a Strategy Inspired by Chemical Network Analysis.Journal of the American Chemical Society · 2019Article
- Synthesis and biological evaluation of (±)-hippolachnin and analogs.The Journal of antibiotics · 2019Article
- A Copper-Mediated Conjugate Addition Approach to Analogues of Aconitine-Type Diterpenoid Alkaloids.The Journal of organic chemistry · 2018Article
- A Benzyne Insertion Approach to Hetisine-Type Diterpenoid Alkaloids: Synthesis of Cossonidine (Davisine).Journal of the American Chemical Society · 2018Article
- A Unifying Synthesis Approach to the CJournal of the American Chemical Society · 2017Article
- Magnesiate Addition/Ring-Expansion Strategy To Access the 6-7-6 Tricyclic Core of Hetisine-Type COrganic letters · 2017Article
- Recent Advances in Substrate-Controlled Asymmetric Cyclization for Natural Product Synthesis.Molecules (Basel, Switzerland) · 2017Review
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Authors and funding
7 authors.
Funding
Abstract
The denudatine-type diterpenoid alkaloids cochlearenine, N-ethyl-1α-hydroxy-17-veratroyldictyzine, and paniculamine have been synthesized for the first time (25, 26, and 26 steps from 16, respectively). These syntheses take advantage of a common intermediate (8) that we have previously employed in preparing aconitine-type natural products. The syntheses reported herein complete the realization of a unified strategy for the preparation of C20, C19, and C18 diterpenoid alkaloids.
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