Evidence map›Paper›PMID 27525232›Full record

ArticleThe Korean journal of thoracic and cardiovascular surgery2016

Twenty-Year Experience of Heart Transplantation: Early and Long-Term Results.

Jae-Hong Lee, Sang Yoon Yeom, Ho Young Hwang, Jae-Woong Choi, Hyun-Jai Cho, Hae-Young Lee, Jae-Hak Huh, Ki-Bong Kim

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Article in The Korean journal of thoracic and cardiovascular surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 · Its place in the literature

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3 citing papers in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Jae-Hong LeeDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Hospital.
Sang Yoon YeomDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Hospital.
Ho Young HwangDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Hospital.
Jae-Woong ChoiDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Hospital.
Hyun-Jai ChoDepartment of Internal Medicine and Cardiovascular Center, Seoul National University Hospital.
Hae-Young LeeDepartment of Internal Medicine and Cardiovascular Center, Seoul National University Hospital.
Jae-Hak HuhDepartment of Thoracic and Cardiovascular Surgery, Myongji Hospital, Seonam University College of Medicine.
Ki-Bong KimDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Hospital.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe evaluated early and long-term results after heart transplantation (HTPL).

methodsOne hundred five consecutive patients (male:female=80:25) who underwent HTPL between 1994 and 2013 were enrolled. Based on the changes in immunosuppressive regimen, the study patients were divided into two groups. Early and long-term clinical outcomes were evaluated and compared between the patients who underwent HTPL before (group E, n=41) and after July 2009 (group L, n=64). The group L patients were older (p<0.001), had higher incidence of hypertension (p=0.001) and chronic kidney disease (p<0.001), and more frequently needed preoperative mechanical ventilation (p=0.027) and mechanical circulatory support (p=0.014) than the group E patients.

resultsOverall operative mortality was 3.8%, and postoperative morbidities included acute kidney injury (n=31), respiratory complications (n=16), reoperation for bleeding (n=15) and wound complications (n=10). There were no significant differences in early results except acute kidney injury between group E and group L patients. Overall survival rates at 1, 5, and 10 years were 83.8%, 67.7%, and 54.9%, respectively, with no significant difference between the two patient groups. Rejection-free rates at 1 and 5 years were 63.0% and 59.7%, respectively; rates were significantly higher in group L than in group E (p<0.001).

conclusionDespite increased preoperative comorbidities, group L patients showed similar early and long-term outcomes and significantly higher rejection-free rates when compared with group E patients.

Indexed as

HeartOutcome assessmentTransplantation

Identifiers

PMID27525232
PMCPMC4981225

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