ArticleNeural plasticity2016
Correlation between Motor Cortex Excitability Changes and Cognitive Impairment in Vascular Depression: Pathophysiological Insights from a Longitudinal TMS Study.
Article in Neural plasticity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Transcranial magnetic stimulation neurophysiology of patients with major depressive disorder: a systematic review and meta-analysis.Psychological medicine · 2021Pooled it
- Cortical inhibition, facilitation and plasticity in late-life depression: effects of venlafaxine pharmacotherapy.Journal of psychiatry & neuroscience : JPN · 2021Trial
- Neuromodulation Techniques in Chronic Cerebral Hypoperfusion: Mechanisms and Therapeutic Advances.CNS neuroscience & therapeutics · 2026Review
- Antidepressant and Related Neurobiological and Neurophysiological Effects of Add-On Transcranial Direct Current Stimulation in Major Depressive Disorder with Residual Symptoms: A Randomized, Double-Blind Clinical Trial Protocol.Methods and protocols · 2025Article
- Effect of Repetitive Transcranial Magnetic Stimulation on Neurocognitive Functions in Moderate and Severe Depression: A Follow-up Study.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2025Article
- Repetitive Transcranial Magnetic Stimulation (rTMS) in Mild Cognitive Impairment: Effects on Cognitive Functions-A Systematic Review.Journal of clinical medicine · 2023Review
- Gamma-glutamyl transferase levels are associated with the occurrence of post-stroke cognitive impairment: a multicenter cohort study.BMC neurology · 2022Article
- Explore the correlation between cerebral vessel characteristics with cognitive impairment among elder individuals: a community study from China.BMC neurology · 2021Article
- Chronic Anxiety- and Depression-Like Behaviors Are Associated With Glial-Driven Pathology Following Repeated Blast Induced Neurotrauma.Frontiers in behavioral neuroscience · 2021Article
- Clinical and Electrophysiological Hints to TMS in De Novo Patients with Parkinson's Disease and Progressive Supranuclear Palsy.Journal of personalized medicine · 2020Article
- Impaired cerebral hemodynamics in late-onset depression: computed tomography angiography, computed tomography perfusion, and magnetic resonance imaging evaluation.Quantitative imaging in medicine and surgery · 2020Article
- Vascular depression for radiology: A review of the construct, methodology, and diagnosis.World journal of radiology · 2020Review
- Update on the Neurobiology of Vascular Cognitive Impairment: From Lab to Clinic.International journal of molecular sciences · 2020Review
- Association of oral dysbiosis with oral cancer development.Oncology letters · 2020Review
- The Influence of Nonpharmacological Complex Therapy Conducted at a Community Day-Care Center on Cognitive function and Mood in Older Adults.Risk management and healthcare policy · 2020Article
- Evaluation of White Matter Integrity Utilizing the DELPHI (TMS-EEG) System.Frontiers in neuroscience · 2020Article
- Evaluation and Treatment of Vascular Cognitive Impairment by Transcranial Magnetic Stimulation.Neural plasticity · 2020Review
- The analysis of miRNA expression profiling datasets reveals inverse microRNA patterns in glioblastoma and Alzheimer's disease.Oncology reports · 2019Article
- Changes of motor cortical excitability and response inhibition in patients with obsessive–compulsive disorderJournal of psychiatry & neuroscience : JPN · 2019Article
- Impact of yoga based lifestyle intervention on psychological stress and quality of life in the parents of children with retinoblastoma.Annals of neurosciences · 2019Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Transcranial magnetic stimulation (TMS) highlighted functional changes in dementia, whereas there are few data in patients with vascular cognitive impairment-no dementia (VCI-ND). Similarly, little is known about the neurophysiological impact of vascular depression (VD) on deterioration of cognitive functions. We test whether depression might affect not only cognition but also specific cortical circuits in subcortical vascular disease. Methods. Sixteen VCI-ND and 11 VD patients, age-matched with 15 controls, underwent a clinical-cognitive, neuroimaging, and TMS assessment. After approximately two years, all participants were prospectively reevaluated. Results. At baseline, a significant more pronounced intracortical facilitation (ICF) was found in VCI-ND patients. Reevaluation revealed an increase of the global excitability in both VCI-ND and VD subjects. At follow-up, the ICF of VCI-ND becomes similar to the other groups. Only VD patients showed cognitive deterioration. Conclusions. Unlike VD, the hyperfacilitation found at baseline in VCI-ND patients suggests enhanced glutamatergic neurotransmission that might contribute to the preservation of cognitive functioning. The hyperexcitability observed at follow-up in both groups of patients also indicates functional changes in glutamatergic neurotransmission. The mechanisms enhancing the risk of dementia in VD might be related either to subcortical vascular lesions or to the lack of compensatory functional cortical changes.
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