Evidence map›Paper›PMID 27525093›Full record

ArticleClinical case reports2016

GM-CSF as successful salvage therapy of metamizole (dipyrone)-induced agranulocytosis with Fournier's gangrene and severe septic shock in an adolescent.

Annegret Winkler, Silke Kietz, Hagen Bahlmann, Gunel Jafarzade, Holger N Lode, Matthias Heckmann

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Annegret WinklerDivision of Neonatology and Pediatric Intensive Care Department of Pediatrics and Adolescent Medicine Medical University of Greifswald Greifswald Germany.
Silke KietzDivision of Pediatric Hematology and Oncology Department of Pediatrics and Adolescent Medicine Medical University of Greifswald Greifswald Germany.
Hagen BahlmannDivision of Neonatology and Pediatric Intensive Care Department of Pediatrics and Adolescent Medicine Medical University of Greifswald Greifswald Germany.
Gunel JafarzadeDivision of Pediatric Surgery Department of Pediatrics and Adolescent Medicine Medical University of Greifswald Greifswald Germany.
Holger N LodeDivision of Pediatric Hematology and Oncology Department of Pediatrics and Adolescent Medicine Medical University of Greifswald Greifswald Germany.
Matthias HeckmannDivision of Neonatology and Pediatric Intensive Care Department of Pediatrics and Adolescent Medicine Medical University of Greifswald Greifswald Germany.
Universität Greifswald · DEUniversitätsmedizin Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes the successful use of granulocyte and macrophage colony-stimulating factor as salvage therapy and an alternative to hematopoietic stem cell transplantation in a 14-year-old adolescent with metamizole (dipyrone)-induced agranulocytosis and severe septic shock.

Indexed as

Agranulocytosisfilgrastimmetamizole (dipyrone)sargramostimseptic shock

Identifiers

PMID27525093
PMCPMC4974437
OpenAlexW2500796190

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.