Evidence map›Paper›PMID 27525014›Full record

ArticleAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2016

Reduced work/academic performance and quality of life in patients with allergic rhinitis and impact of allergen immunotherapy.

A Roger, E Arcalá Campillo, M C Torres, C Millan, I Jáuregui, E Mohedano, S Liñan, P Verdu, N Rubira, M Santaolalla and 3 more

Open access · goldAbstract read
In one paragraph

Article in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
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  4. Review
  5. Evaluation ofMolecules (Basel, Switzerland) · 2024
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  10. Review
  11. Observational
  12. Article
  13. HealthSWEDE: costs with sublingual immunotherapy-a Swedish questionnaire study.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2021
    Article
  14. Article
  15. Review
  16. Article
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  18. Article
  19. Catgut Implantation at Acupoint Reduces Immune Reaction in a Rat Model of Allergic Rhinitis.Evidence-based complementary and alternative medicine : eCAM · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 1 country.

A RogerAllergy Unit, Germans Trias i Pujol Hospital, Badalona, Spain.
E Arcalá CampilloAlergólogo. Consulta Privada, Jaén, Spain.
M C TorresUnidad de Alergia, Hospital Casa de Salud, Valencia, Spain.
C MillanUnidad de Alergia, Hospital Jerez de la Frontera, Jerez de la Frontera, Spain.
I JáureguiServicio de Alergia, Hospital Universitario de Basurto, Bilbao, Spain.
E MohedanoServicio de Alergia, Hospital Universitario de Fuenlabrada, Fuenlabrada, Spain.
S LiñanNeumología Pediátrica, Hospital de Nens de Barcelona, Barcelona, Spain.
P VerduServicio de Alergia, Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain.
N RubiraUnidad de Alergia, Centro Sanitario C Mora, Sant Cugat, Barcelona, Spain.
M SantaolallaServicio de Alergia, Hospital Universitario de Sanchinarro, Madrid, Spain.
P GonzálezServicio de Alergia, Hospital General Universitario de Alicante, Alicante, Spain.
A OrovitgUnidad de Alergia, Hospital Viamed Santa Angela de la Cruz, Seville, Spain.
E VillarrubiaHealth Outcomes Research Department, 3D Health Research, Balmes 152 6º 2ª, 08008 Barcelona, Spain.
Consorci Sanitari Garraf · ESHospital Casa de Salud · ESHospital de Basurto · ESHospital de Nens de Barcelona · ESHospital General Universitario de Alicante Doctor Balmis · ESHospital Jerez Puerta del Sur · ESHospital San Juan de la Cruz · ESHospital Universitari Germans Trias i Pujol · ESHospital Universitario de Fuenlabrada · ESHospital Universitario de Gran Canaria Doctor Negrín · ESHospital Universitario HM Sanchinarro · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAllergic rhinitis (AR) is characterised by burdensome nasal and/or ocular symptoms. This inflammatory disease can be debilitating and thus result in considerable health-related and economic consequences.

methodsIn a cross-sectional study, adult subjects with AR (N = 683) completed three allergy-specific questionnaires that assessed the impact of AR on the work/academic performance, daily activities, health-related quality of life (HRQOL), and satisfaction with allergen immunotherapy (AIT). Regression analyses were used to examine the associations between several clinical variables and the patient-reported outcomes.

resultsTotal loss of productivity was 21.0 and 21.2 % for employed and student patients, respectively, whereas the impairment of daily activities was 22.0 %. The mean overall HRQOL score was 1.94 ± 1.29 (on the scale of 0-6 points). Global score for satisfaction with AIT was 65.5 ± 24.8 (on a 0-100 scale). Simple regression analysis found statistically significant associations between loss of work and academic productivity, impairment of daily activities and the type and severity of AR. AIT was a protective factor. The persistent and more severe types of AR and lack of AIT contributed to the worsening of HRQOL.

conclusionsAR (the persistent and more severe form of the disease) has an impact on functional characteristics of adult patients in Spain. AIT might reduce the effect of this disease on the work/academic performance and HRQOL. Trial registration Retrospectively registered.

Indexed as

Allergen immunotherapyAllergic rhinitisDaily activitiesProductivityQuality of life

Identifiers

PMID27525014
PMCPMC4982204
OpenAlexW2511177693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.