ArticleInternational journal of epidemiology2017
Adiposity in relation to age at menarche and other reproductive factors among 300 000 Chinese women: findings from China Kadoorie Biobank study.
Article in International journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Adiposity and risk of breast cancer in 280 000 Chinese women: a prospective cohort study.International journal of epidemiology · 2026Observational
- Early menarche and late menopause and their association with hypertension among Bangladeshi women: a community-based cross-sectional study in Dhaka, Bangladesh.BMC women's health · 2026Article
- Adiposity and reproductive characteristics across the lifespan: a multi-ethnic population-based study in Northwest China.Reproductive health · 2026Article
- Age at menarche and general and abdominal obesity in older Brazilian women: ELSI-Brazil.Revista de saude publica · 2026Article
- Association between BMI trajectories and metabolic syndrome in postmenopausal women: a cross-sectional study from NHANES 1999-2018.BMC public health · 2025Article
- Age at Menarche and Coronary Artery Disease Risk: Divergent Associations With Different Sources of Variation.The Journal of clinical endocrinology and metabolism · 2025Article
- Identification of loci associated with women's reproductive traits and exploration of a shared genetic basis with obesity.Human genomics · 2025Article
- The association between age at menopause and bone health in Southwest China women: mediation effect of body mass index.BMC public health · 2024Article
- Exploring the Influence of Age at Menarche on Metabolic Syndrome and Its Components Across Different Women's Birth Cohorts.Endocrinology, diabetes & metabolism · 2024Article
- Association of Age at Menarche with General and Abdominal Obesity in Young Women.Medicina (Kaunas, Lithuania) · 2024Article
- Prevalence and risk factors of thyroid nodules in breast cancer women with different clinicopathological characteristics: a cross-sectional study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024Article
- Reproductive factors and risk of lung cancer among 300,000 Chinese female never-smokers: evidence from the China Kadoorie Biobank study.BMC cancer · 2024Article
- Mother's age at menarche is associated with odds of preterm delivery: A case-control study.BJOG : an international journal of obstetrics and gynaecology · 2024Article
- Early puberty: a review on its role as a risk factor for metabolic and mental disorders.Frontiers in pediatrics · 2024Review
- Associations of age at first birth and lifetime parity with weight and adiposity across midlife in women from Project Viva.Obesity (Silver Spring, Md.) · 2023Article
- [Secular trends of age at menarche and age at menopause in women born since 1951 from a county of Shandong Province, China].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Article
- Late age at menopause positively associated with obesity-mediated hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Obesity indicators as mediators of the association between age at menopause and blood pressure values.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- The relationship of reproductive factors with adiposity and body shape indices changes overtime: findings from a community-based study.Journal of translational medicine · 2023Article
- Association of age at menarche with valvular heart disease: An analysis based on electronic health record (CREAT2109).Frontiers in cardiovascular medicine · 2023Article
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18 authors.
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Abstract
Background: Adiposity is increasing rapidly in China but little is known about the relevance to it of women's reproductive factors, which differ inter-generationally and from that in the West. We assess associations of adiposity with life-course reproductive factors in Chinese women. Methods: In 2004-08, the nationwide China Kadoorie Biobank recruited 303 000 women aged 30-79 (mean 50) years from 10 diverse regions. Multivariable linear regression was used to examine associations of reproductive factors (e.g. age at menarche/first birth/menopause, parity, breastfeeding and reproductive years) with measures of general [e.g. body mass index (BMI)] and central [e.g. waist circumference (WC)] adiposity in adulthood. Results: Overall, the mean BMI was 23.7 (standard deviation 3.3) kg/m 2 , mean age at menarche was 15 (2) years and nearly all had given birth (99%) and breastfed children (98%). Adiposity was associated inversely with age at menarche and at first birth, with 0.19 and 0.05 kg/m 2 lower BMI and 0.38 and 0.12 cm lower WC per 1-year delay respectively ( P < 0.001). Among 128 259 post-menopausal women, adiposity was associated positively with age at menopause and reproductive years, with 0.05 and 0.07 kg/m 2 higher BMI and 0.12 and 0.17 cm higher WC per 1-year increase, respectively ( P < 0.001). The proportion with overweight/obesity had similar associations with these reproductive factors. Adiposity had a non-linear positive association with parity, but no association with breastfeeding duration. Conclusion: Among Chinese women, earlier age at menarche and at first birth, later age at menopause and longer reproductive years were independently associated with increased adiposity late in life.
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