ReviewClinics in perinatology2016
Fetal Physiology and the Transition to Extrauterine Life.
Review in Clinics in perinatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04964531 (Left Ventricular Remodeling After Transcatheter Closure of the Patent Ductus Arteriosus. Comparative Study Between Different Age Groups), which is not on this map. Cited by 132 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Left Ventricular Remodeling After Transcatheter Closure of the Patent Ductus Arteriosus. Comparative Study Between Different Age Groups
Who cites it
132 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Multisensory stimulation for promoting development and preventing morbidity in preterm infants.The Cochrane database of systematic reviews · 2026Pooled it
- Reference ranges of blood glucose values in healthy term neonates in their first days of life: a systematic review and meta-analysis.European journal of pediatrics · 2025Pooled it
- A Review on the Vagus Nerve and Autonomic Nervous System During Fetal Development: Searching for Critical Windows.Frontiers in neuroscience · 2021Pooled it
- Prenatal prediction of neonatal haemodynamic adaptation after maternal hyperoxygenation.BMC pregnancy and childbirth · 2020Trial
- Care of the Newborn and Cord During the Third Stage of Labour (Scientific Impact Paper No. 78).BJOG : an international journal of obstetrics and gynaecology · 2026Review
- Effects of surfactant therapy, ventilation, and patent ductus arteriosus on regional pulmonary and cerebral oxygenation in preterm infants using near-infrared spectroscopy.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Understanding physiological adaptations of pregnancy to the chronic hypoxia of high altitude to inform obstetrical and neonatal care.Physiological reviews · 2026Review
- Article
- Transcriptional dynamics of the murine heart during perinatal development at single-cell resolution.Biology open · 2026Article
- Reference Intervals of Hematological Parameters Among Healthy Newborns in Eastern Sudan: A Hospital-Based Cross-Sectional Study.Children (Basel, Switzerland) · 2026Article
- Mono-dimensional, two-dimensional and Doppler echocardiographic measurements in healthy Standardbred neonatal foals in the first 5 days of life.Equine veterinary journal · 2026Article
- Embracing non-linearity in human ageing.Nature reviews. Genetics · 2026Review
- Heart Rate Variability in Newborns From Diabetic Mothers: Clinical Application and Significance.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026Review
- Monitoring Parameters During the Immediate Postnatal Transition Period and Inflammatory Markers in the First Two Days After Birth-A Retrospective Data Analysis.Children (Basel, Switzerland) · 2026Article
- Development of striated muscle microvasculature across the perinatal period in lambs.The Journal of physiology · 2026Article
- Hemodynamics and cerebral oxygenation in the neonatal transition: a prospective pilot study.Clinical and experimental pediatrics · 2026Article
- Stimulate, Ventilate Collaborate-A Qualitative Study Underpinning the Development of an Educational Guide to Newborn Resuscitation for Midwifery Students.Nursing open · 2026Article
- Impact of cerebral oxygenation-guided resuscitation during immediate postnatal transition on brain injury and brain growth detected by MRI in very preterm neonates: a secondary outcome analysis of the multicenter randomized phase 3 clinical COSGOD III trial.Italian journal of pediatrics · 2026Article
- TRAP Sequence Clinical Case: Is a Single Umbilical Artery a Protective Ultrasound Marker for Fetal Heart Failure Development.Pediatric cardiology · 2026Article
- Comparing peripheral limb and forehead vital sign monitoring in newborn infants at birth.Pediatric research · 2026Article
72 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The physiology of the fetus is fundamentally different from the neonate, with both structural and functional distinctions. The fetus is well-adapted to the relatively hypoxemic intrauterine environment. The transition from intrauterine to extrauterine life requires rapid, complex, and well-orchestrated steps to ensure neonatal survival. This article explains the intrauterine physiology that allows the fetus to survive and then reviews the physiologic changes that occur during the transition to extrauterine life. Asphyxia fundamentally alters the physiology of transition and necessitates a thoughtful approach in the management of affected neonates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.