Evidence map›Paper›PMID 27523800›Full record

ArticleStatistics in medicine2016

Bayesian joint ordinal and survival modeling for breast cancer risk assessment.

C Armero, C Forné, M Rué, A Forte, H Perpiñán, G Gómez, M Baré

Abstract read
In one paragraph

Article in Statistics in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

C ArmeroDepartment of Statistics and Operational Research, Universitat de València, Doctor Moliner, 50, 46100, Burjassot, Spain. Carmen.Armero@uv.es.
C FornéDepartment of Basic Medical Sciences, Universitat de Lleida-IRBLleida, Avda. Rovira Roure, 80, 25198, Lleida, Spain.
M RuéDepartment of Basic Medical Sciences, Universitat de Lleida-IRBLleida, Avda. Rovira Roure, 80, 25198, Lleida, Spain.
A ForteDepartment of Statistics and Operational Research, Universitat de València, Doctor Moliner, 50, 46100, Burjassot, Spain.
H PerpiñánDepartment of Statistics and Operational Research, Universitat de València, Doctor Moliner, 50, 46100, Burjassot, Spain.
G GómezDepartment of Statistics and Operations Research, Universitat Politècnica de Catalunya, Barcelona, Spain.ORCID 0000-0003-4252-4884
M BaréClinical Epidemiology and Cancer Screening, Corporació Sanitària Parc Taulí-UAB, Sabadell, Parc Taulí s/n, Sabadell, 08208, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We propose a joint model to analyze the structure and intensity of the association between longitudinal measurements of an ordinal marker and time to a relevant event. The longitudinal process is defined in terms of a proportional-odds cumulative logit model. Time-to-event is modeled through a left-truncated proportional-hazards model, which incorporates information of the longitudinal marker as well as baseline covariates. Both longitudinal and survival processes are connected by means of a common vector of random effects. General inferences are discussed under the Bayesian approach and include the posterior distribution of the probabilities associated to each longitudinal category and the assessment of the impact of the baseline covariates and the longitudinal marker on the hazard function. The flexibility provided by the joint model makes possible to dynamically estimate individual event-free probabilities and predict future longitudinal marker values. The model is applied to the assessment of breast cancer risk in women attending a population-based screening program. The longitudinal ordinal marker is mammographic breast density measured with the Breast Imaging Reporting and Data System (BI-RADS) scale in biennial screening exams. © 2016 The Authors. Statistics in Medicine Published by John Wiley & Sons Ltd.

Indexed as

Bayes TheoremBreastBreast DensityBreast NeoplasmsFemaleHumansRisk AssessmentBI-RADS scaleLatent processleft-truncated proportional-hazards modelProportional-odds cumulative logit model

Identifiers

PMID27523800
PMCPMC5129536

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.