ReviewCurrent diabetes reports2016
The Role of the Intestinal Microbiome in Type 1 Diabetes Pathogenesis.
Review in Current diabetes reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 57 citations in OpenAlex.
- Diet, gut microbiome, and type 1 diabetes: from risk to translational opportunity.Gut microbes · 2026Review
- Joint modeling of longitudinal biomarker and survival outcomes with the presence of competing risk in the nested case-control studies with application to the TEDDY microbiome dataset.Bioinformatics (Oxford, England) · 2026Article
- Integrating bioinformatic prediction and the "gut microbiota-inflammation-skin axis" to decipher the mechanisms of quercetin (fromFrontiers in immunology · 2026Article
- Gut Virome and Aging: Phage-Driven Microbial Stability and Immune Modulation.Aging and disease · 2025Review
- Gut microbiome shifts in people with type 1 diabetes are associated with glycaemic control: an INNODIA study.Diabetologia · 2024Article
- Gut microbiota mediated T cells regulation and autoimmune diseases.Frontiers in microbiology · 2024Review
- The role of GABA in type 1 diabetes.Frontiers in endocrinology · 2024Review
- Role of the gut microbiome in chronic diseases: a narrative review.European journal of clinical nutrition · 2022Review
- The Human Virome: Viral Metagenomics, Relations with Human Diseases, and Therapeutic Applications.Viruses · 2022Review
- New Wild-TypeMicroorganisms · 2022Article
- Systemic Evaluation of the Effect of Diabetes Mellitus on Breast Cancer in a Mouse Model.Frontiers in oncology · 2022Article
- Gut Microbial Antigenic Mimicry in Autoimmunity.Frontiers in immunology · 2022Review
- Detection ofFrontiers in veterinary science · 2022Article
- Natural Ingredients from Medicine Food Homology as Chemopreventive Reagents against Type 2 Diabetes Mellitus by Modulating Gut Microbiota Homoeostasis.Molecules (Basel, Switzerland) · 2021Review
- Effect of formaldehyde exposure on bacterial communities in simulating indoor environments.Scientific reports · 2021Article
- Holistic perspective of the role of gut microbes in diabetes mellitus and its management.World journal of diabetes · 2021Review
- Association of diabetes and microbiota: An update.Saudi journal of biological sciences · 2021Review
- Functional maturation of immature β cells: A roadblock for stem cell therapy for type 1 diabetes.World journal of stem cells · 2021Review
- The Gut Microbiota Profile According to Glycemic Control in Type 1 Diabetes Patients Treated with Personal Insulin Pumps.Microorganisms · 2021Article
- Common Inflammatory Mechanisms in COVID-19 and Parkinson's Diseases: The Role of Microbiome, Pharmabiotics and Postbiotics in Their Prevention.Journal of inflammation research · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gastrointestinal system represents one of the largest interfaces between the human internal microenvironment and the external world. This system harbors trillions of commensal bacteria that reside in symbiosis with the host. Intestinal bacteria play a crucial role in maintaining systemic and intestinal immune and metabolic homeostasis because of their effect on nutrient absorption and immune development and function. Recently, altered gut bacterial composition (dysbiosis) was hypothesized to be involved in mechanisms through which islet autoimmunity is triggered. Evidence from animal models indicates that alterations in the gut bacterial composition precede disease onset, thus implicating a causal role for the gut microbiome in islet destruction. However, it remains unclear whether dysbiosis is directly linked to the mechanisms of human type 1 diabetes (T1D). In this review, we discuss data implicating the gut microbiota in disease progression with an emphasis on our recent studies performed in humans and in rodent models of T1D.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.