ReviewFertility and sterility2016
Morphologic and molecular changes in the placenta: what we can learn from environmental exposures.
Review in Fertility and sterility, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 48 citations in OpenAlex.
- Bridging exposure and disease: serum hormones as potential mediators between PBDEs and preeclampsia.BMC pregnancy and childbirth · 2026Article
- Mouse placentae generated by in vitro fertilization exhibit altered gene expression, activated hypoxia responses, and reduced fitness†.Biology of reproduction · 2026Article
- Effects of an aryl hydrocarbon receptor ligand on human trophoblast cell development.Human reproduction (Oxford, England) · 2025Article
- Aryl Hydrocarbon Receptor Activation Drives 2-Methoxy Estradiol Secretion in Human Trophoblast Stem Cell Development.bioRxiv : the preprint server for biology · 2025Article
- Placental expression and methylation of angiogenic factors in assisted reproductive technology pregnancies from India.Epigenomics · 2025Article
- Risk Factors of Marginal Cord Insertion in Singleton Pregnancies: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Risk Factors of Velamentous Cord Insertion in Singleton Pregnancies-A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- [Metformin ameliorates PM2.5-induced functional impairment of placental trophoblasts by inhibiting ferroptosis].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- Article
- The impact of HIV and ART exposure during pregnancy on fetal growth: a prospective study in a South African cohort.BMC pregnancy and childbirth · 2023Article
- Mono(2-ethylhexyl) phthalate induces transcriptomic changes in placental cells based on concentration, fetal sex, and trophoblast cell type.Archives of toxicology · 2023Article
- Endocrine-Disrupting Effects of Bisphenol A on the Cardiovascular System: A Review.Journal of xenobiotics · 2022Review
- Praegnatio Perturbatio-Impact of Endocrine-Disrupting Chemicals.Endocrine reviews · 2021Review
- Concentrations of persistent organic pollutants in maternal plasma and epigenome-wide placental DNA methylation.Clinical epigenetics · 2020Article
- DNA methylation status of imprintedAnnals of translational medicine · 2020Article
- Placenta Disrupted: Endocrine Disrupting Chemicals and Pregnancy.Trends in endocrinology and metabolism: TEM · 2020Review
- Developmental programming: Prenatal bisphenol A treatment disrupts mediators of placental function in sheep.Chemosphere · 2020Article
- Endocrine-Disrupting Chemicals in Human Fetal Growth.International journal of molecular sciences · 2020Review
- Chemical Contaminants from Plastics in the Animal Environment.Journal of the American Association for Laboratory Animal Science : JAALAS · 2019Article
- In vitro fertilization alters phospholipid profiles in mouse placenta.Journal of assisted reproduction and genetics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
In mammals, the extraembryonic tissues, which include the placenta, are crucial for embryonic development and growth. Because the placenta is no longer needed for postnatal life, however, it has been relatively understudied as a tissue of interest in biomedical research. Recently, increased efforts have been placed on understanding the placenta and how it may play a key role in human health and disease. In this review, we discuss two very different types of environmental exposures: assisted reproductive technologies and in utero exposure to endocrine-disrupting chemicals. We summarize the current literature on their effects on placental development in both rodent and human, and comment on the potential use of placental biomarkers as predictors of offspring health outcomes.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.