Evidence map›Paper›PMID 27522221›Full record

ReviewJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2017

A broader look at ammonia production, excretion, and transport in fish: a review of impacts of feeding and the environment.

Carol Bucking

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. Response of epithelial cell lines from the rainbow trout gut and gill to ammonia.In vitro cellular & developmental biology. Animal · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Chronic Ammonia Stress in Chinese Perch (Antioxidants (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Ammonia Increases the Stress of the Amazonian GiantAnimals : an open access journal from MDPI · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Metabolic Hepatic Disorders Caused by Ciguatoxins in Goldfish (Animals : an open access journal from MDPI · 2022
    Article
  17. Article
  18. Impacts of low salinity exposure and antibiotic application on gut transport activity in the Pacific spiny dogfish, Squalus acanthias suckleyi.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2020
    Article
  19. Article
  20. Post-prandial physiology and intestinal morphology of the Pacific hagfish (Eptatretus stoutii).Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Carol BuckingDepartment of Biology, Farquharson Life Science Building, York University, Toronto, ON, M3J 1P3, Canada. cbucking@yorku.ca.ORCID http://orcid.org/0000-0003-3655-426X
York University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For nearly a century, researchers have studied ammonia production and excretion in teleost fish. Stemming from past investigations a body of knowledge now exists on various aspects including biochemical mechanisms of ammonia formation and specific routes and tissues used for ammonia transport, culminating in a current detailed theoretical model of branchial transport, including the molecular identities of the moieties involved. However, typical studies examining ammonia balance use routine laboratory conditions and fasted fish. While avoiding additional variables that influence nitrogen balance, these studies are arguably idealistic and do not reflect the natural variety of conditions that fish encounter. Further studies have revealed the impacts of extrinsic factors (e.g. salinity, pH, temperature) on ammonia handling in fasted fish whereas others have explored intrinsic factors, such as life history and developmental impacts. One routine challenge for ammonia balance that fish encounter is feeding and digestion. Fortunately, many new studies have revealed the impact of feeding and digestion on several aspects of ammonia balance; from production to excretion and to transport, and several have done so incorporating supplemental extrinsic and/or intrinsic factors. Together, these complex studies reveal realistic responses to multifactorial challenges encountered by animals in the wild and begin to provide a holistic view of ammonia balance in freshwater teleost fish.

Indexed as

AmmoniaAnimalsEatingEnvironmentFishesAmmoniaAmino acid metabolismGillIntestineKidneyNitrogen metabolismSalinitySkinTemperature

Identifiers

PMID27522221
OpenAlexW2509579761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.