ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2016
Measuring health-related quality of life in patients with conservatively managed stage 5 chronic kidney disease: limitations of the Medical Outcomes Study Short Form 36: SF-36.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Quality of life in patients with hypoparathyroidism receiving standard treatment: an updated systematic review.Endocrine · 2024Pooled it
- The anchor design of anchor-based method to determine the minimal clinically important difference: a systematic review.Health and quality of life outcomes · 2023Pooled it
- Exercise training for adults undergoing maintenance dialysis.The Cochrane database of systematic reviews · 2022Pooled it
- Effects of home-based exercise on physical function and health-related quality of life in older patients with pre-dialysis chronic kidney disease: a single-center randomized controlled trial.Clinical and experimental nephrology · 2026Trial
- Effects of Dapagliflozin on Health-Related Quality of Life in Patients with CKD.Journal of the American Society of Nephrology : JASN · 2026Article
- Observational
- Chronic kidney disease progression, long-term nursing care burden and habitual physical activity: an observational study in Japan.BMJ public health · 2025Article
- Identifying predictors of resilience to stressors in single-arm studies of pre-post change.Biostatistics (Oxford, England) · 2024Article
- Research on evaluation indicators of healthspan for veterans: A single-center exploratory study.Pakistan journal of medical sciences · 2024Article
- Health-related quality of life and symptom burden in patients on haemodialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Article
- Thyroidectomy for Euthyroid Patients with Hashimoto Disease and Persistent Symptoms: An Observational, Postrandomization Study.Journal of thyroid research · 2024Article
- Observational
- Validity and reliability of the Patient-Reported Outcomes Measurement Information System (PROMIS®) using computerized adaptive testing in patients with advanced chronic kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023Article
- The relationship between 19-year trends in medication use and changes in physical function among women in the mid-life: A Study of Women's Health Across the Nation pharmacoepidemiology study.Pharmacoepidemiology and drug safety · 2022Article
- The relationship between chronic kidney disease-associated pruritus and health-related quality of life: a systematic review.Clinical kidney journal · 2022Article
- Clinical practice guideline exercise and lifestyle in chronic kidney disease.BMC nephrology · 2022Article
- Factors Associated With 10-Year Declines in Physical Health and Function Among Women During Midlife.JAMA network open · 2022Article
- Article
- Impact of the COVID-19 pandemic on symptoms of anxiety and depression and health-related quality of life in older patients with chronic kidney disease.BMC geriatrics · 2021Article
- Quality of life for kidney transplant recipients and hemodialysis patients in Palestine: a cross-sectional study.BMC nephrology · 2021Article
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Authors and funding
3 authors.
Funding
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Abstract
purposeChronic kidney disease (CKD) negatively affects health-related quality of life (HRQoL), which is often measured using the Medical Outcomes Study Short Form 36 (SF-36) questionnaire. However, the adequacy of SF-36 in this population has not been reported. We aimed to determine floor and ceiling effects and responsiveness to change of SF-36 in patients with conservatively managed stage 5 CKD.
methodsSF-36 data were collected prospectively. Floor and ceiling effects were estimated for each SF-36 scale and summary measure based on raw scores. The minimal clinically important difference (MCID) was estimated using a combination of anchor-based and distribution-based methods. Responsiveness to change was assessed by comparing MCID for each scale and summary measure to its smallest detectable change.
resultsSF-36 data were available for 73 of the 74 study participants. Using baseline data, floor and/or ceiling effects were detected for 3 of the 8 SF-36 scales. The anchor-based estimation of MCID based on differences in baseline functional status yielded the most reliable results. For the physical component summary, MCID was estimated at 5.7 points. Whilst the two SF-36 summary measures were responsive to change and free of floor and/or ceiling effects, six of the eight scales were not.
conclusionsThis small study of patients with conservatively managed stage 5 CKD found that only the summary measures of SF-36 and 2 of its 8 scales can be used to assess changes in HRQoL over time. These findings suggest that in this population, alternative HRQoL assessment tools should be considered for future studies.
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