Evidence map›Paper›PMID 27522193›Full record

SynthesisCell and tissue banking2016

Disinfection of human skin allografts in tissue banking: a systematic review report.

C Johnston, J Callum, J Mohr, A Duong, A Garibaldi, N Simunovic, O R Ayeni, Bioburden Steering Committee and Skin Working group

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Cell and tissue banking, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Development ofMolecular pharmaceutics · 2023
    Article
  4. Review
  5. Biofilm formation and antibiotic susceptibility of Staphylococcus and Bacillus species isolated from human allogeneic skin.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

C JohnstonCapital Health Regional Tissue Bank, 5788 University Avenue, Room 431 Mackenzie Building, Halifax, NS, B3H 1V7, Canada.
J CallumSunnybrook Health Sciences Centre Blood and Tissue Bank, 2075 Bayview Ave., Room B2 04, Toronto, ON, M4N 3M5, Canada.
J MohrCanadian Blood Services, 270 John Savage Ave., Dartmouth, NS, B3B 0H7, Canada.
A DuongDepartment of Surgery, McMaster University, 293 Wellington St. N, Suite 110, Hamilton, ON, L8L 8E7, Canada.
A GaribaldiDepartment of Surgery, McMaster University, 293 Wellington St. N, Suite 110, Hamilton, ON, L8L 8E7, Canada.
N SimunovicDepartment of Surgery, McMaster University, 293 Wellington St. N, Suite 110, Hamilton, ON, L8L 8E7, Canada.
O R AyeniDepartment of Surgery, McMaster University, 293 Wellington St. N, Suite 110, Hamilton, ON, L8L 8E7, Canada. Ayenif@mcmaster.ca.
Bioburden Steering Committee and Skin Working group
McMaster University · CACanadian Blood Services · CACapital District Health Authority · CAMcMaster University Medical Centre · CASunnybrook Health Science Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of skin allografts to temporarily replace lost or damaged skin is practiced worldwide. Naturally occurring contamination can be present on skin or can be introduced at recovery or during processing. This contamination can pose a threat to allograft recipients. Bacterial culture and disinfection of allografts are mandated, but the specific practices and methodologies are not dictated by standards. A systematic review of literature from three databases found 12 research articles that evaluated bioburden reduction processes of skin grafts. The use of broad spectrum antibiotics and antifungal agents was the most frequently identified disinfection method reported demonstrating reductions in contamination rates. It was determined that the greatest reduction in the skin allograft contamination rates utilized 0.1 % peracetic acid or 25 kGy of gamma irradiation at lower temperatures.

Indexed as

Skin TransplantationTissue BanksAllograftsCell Culture TechniquesDisinfectionHumansSkinSterilizationTransplantation, HomologousBioburdenSkin allograftsSkin decontaminationTissue bankingTissue donation

Identifiers

PMID27522193
PMCPMC5116035
OpenAlexW2513637293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.