ArticleCerebral cortex (New York, N.Y. : 1991)2017
Temporal Evolution of Brain Functional Connectivity Metrics: Could 7 Min of Rest be Enough?
Article in Cerebral cortex (New York, N.Y. : 1991), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A decade of test-retest reliability of functional connectivity: A systematic review and meta-analysis.NeuroImage · 2019Pooled it
- Methylphenidate reorganizes cortical hierarchy through dopaminergic modulation.Nature communications · 2025Trial
- Blunted modulation of hierarchical brain organization in opioid use disorder.Research square · 2026Article
- Individualized functional connectome biomarkers predict clinical symptoms after rTMS treatment in Alzheimer's disease.Translational psychiatry · 2025Article
- Functional brain connectivity of the salience network in alcohol use and anxiety disorders.Journal of affective disorders · 2025Article
- TR(Acking) Individuals Down: Exploring the Effect of Temporal Resolution in Resting-State Functional MRI Fingerprinting.Human brain mapping · 2025Article
- Personalized temporal interference stimulation targeting striatum reduces functional stability and dynamic connectivity variability in the sensorimotor network.Frontiers in neuroscience · 2025Article
- Comparing reliability-based measures of functional connectivity between movie and rest: An ROI-based approach.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Deciphering network dysregulations and temporo-spatial dynamics in disorders of consciousness: insights from minimum spanning tree analysis.Frontiers in psychology · 2024Article
- Reliability and clinical utility of spatially constrained estimates of intrinsic functional networks from very short fMRI scans.Human brain mapping · 2023Article
- Altered Functional Connectivity Density in Type 2 Diabetes Mellitus with and without Mild Cognitive Impairment.Brain sciences · 2023Article
- Frequency-specific coactivation patterns in resting-state and their alterations in schizophrenia: An fMRI study.Human brain mapping · 2022Article
- Pre-diabetes is associated with altered functional connectivity density in cortical regions of the default-mode network.Frontiers in aging neuroscience · 2022Article
- Test-retest reliability of modular-relevant analysis in brain functional network.Frontiers in neuroscience · 2022Article
- The effect of general anesthesia on the test-retest reliability of resting-state fMRI metrics and optimization of scan length.Frontiers in neuroscience · 2022Article
- Alterations in whole-brain dynamic functional stability during memory tasks under dexmedetomidine sedation.Frontiers in neurology · 2022Article
- Surface-Based Connectivity Integration: An atlas-free approach to jointly study functional and structural connectivity.Human brain mapping · 2021Article
- Prognostic neuroimaging biomarkers of trauma-related psychopathology: resting-state fMRI shortly after trauma predicts future PTSD and depression symptoms in the AURORA study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Article
- Topological impact of negative links on the stability of resting-state brain network.Scientific reports · 2021Article
- Measurement reliability for individual differences in multilayer network dynamics: Cautions and considerations.NeuroImage · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Unaccounted temporal dynamics of resting-state functional connectivity (FC) metrics challenges their potential as biomarkers for clinical applications in neuroscience. Here we studied the scan time required to reach stable values for various FC metrics including seed-voxel correlations and spatial independent component analyses (sICA), and for the local functional connectivity density (lFCD), a graph theory metric. By increasing the number of time points included in the analysis, we assessed the effects of scan time on convergence of accuracy, sensitivity, specificity, reproducibility, and reliability of these FC metrics. The necessary scan time to attenuate the effects of the temporal dynamics by 80% varied across connectivity metrics and was shorter for lFCD (7 min) than for FC (11 min) or for sICA (10 min). Findings suggest that the scan time required to achieve stable FC is metric-dependent, with lFCD being the most resilient metric to the effects of temporal dynamics. Thus, the lFCD metric could be particularly useful for pediatric and patient populations who may not tolerate long scans.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.