ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2017
Changes in the Lethality of Frailty Over 30 Years: Evidence From Two Cohorts of 70-Year-Olds in Gothenburg Sweden.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The conceptualisation and measurement of social frailty in older people: an umbrella review.The Journal of frailty & aging · 2025Pooled it
- The relationship between parity and late-life frailty: companion dogs as a preclinical model for evaluating factors that aggravate or mitigate the frailty cost of reproduction.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Longer duration of intact hypothalamic-pituitary-gonadal (HPG) axis buffers the adverse impact of late-life frailty in male dogs.Scientific reports · 2025Article
- Twenty-year trend in comorbidity score among adults aged 50-85 years in Lombardy, Italy: Age-Cohort-Period analysis and future trends.BMJ open · 2025Observational
- Frailty and Mortality Risk Among Dogs with Extreme Longevity: Development and Predictive Validity of a Clinical Frailty Index in the Exceptional Aging in Rottweilers Study.Animals : an open access journal from MDPI · 2024Article
- Secular trends in frailty among community-dwelling 75-95-year-old cohorts over three decades in Helsinki, Finland.Age and ageing · 2024Article
- Longitudinal Quantiles of Frailty Trajectories Considering Death: New Insights into Sex and Cohort Differences in the Reference Curves for Frailty Progression of Older European.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Living Longer But Frailer? Temporal Trends in Life Expectancy and Frailty in Older Swedish Adults.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Frailty before and during austerity: A time series analysis of the English Longitudinal Study of Ageing 2002-2018.PloS one · 2024Article
- Frailty Trends in an Older Veteran Subpopulation 1 Year Prior and Into the COVID-19 Pandemic Using CAN Scores.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2023Article
- Trends in Frailty Between 1990 and 2020 in Sweden Among 75-, 85-, and 95-Year-Old Women and Men: A Nationwide Study from Sweden.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023Article
- Attrition in the Gothenburg H70 birth cohort studies, an 18-year follow-up of the 1930 cohort.Frontiers in epidemiology · 2023Article
- Relationship of body mass index with frailty and all-cause mortality among middle-aged and older adults.BMC medicine · 2022Article
- Effects of age, period, and cohort on the prevalence of frailty in Chinese older adults from 2002 to 2014.Frontiers in public health · 2022Article
- The degree of frailty as a translational measure of health in aging.Nature aging · 2021Review
- Early-Life Socioeconomic Position and the Accumulation of Health-Related Deficits by Midlife in the 1958 British Birth Cohort Study.American journal of epidemiology · 2021Article
- Article
- Trends in Frailty and Its Association With Mortality: Results From the Longitudinal Aging Study Amsterdam, 1995-2016.American journal of epidemiology · 2021Article
- Dementia remains the major predictor of death among octogenarians. A study of two population cohorts of 85-year-olds examined 22 years apart.European journal of epidemiology · 2021Article
- The Prevalence of Frailty Using Three Different Frailty Measurements in Two Finnish Cohorts Born Before and After the Second World War.The journal of nutrition, health & aging · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWith aging, health deficits accumulate: people with few deficits for their age are fit, and those with more are frail. Despite recent reports of improved health in old age, how deficit accumulation is changing is not clear. Our objectives were to evaluate changes over 30 years in the degree of deficit accumulation and in the relationship between frailty and mortality in older adults.
methodsWe analyzed data from two population based, prospective longitudinal cohorts, assembled in 1971-1972 and 2000-2001, respectively. Residents of Gothenburg Sweden, systematically drawn from the Swedish population registry. The 1901-1902 cohort (N = 973) had a response rate of 84.8%; the 1930 cohort (N = 500) had a response rate of 65.1%. A frailty index using 36 deficits was calculated using data from physical examinations, assessments of physical activity, daily, sensory and social function, and laboratory tests. We evaluated mortality over 12.5 years in relation to the frailty index.
resultsMean frailty levels were the same (x¯ = 0.20, p = .37) in the 1901-1902 cohort as in the 1930 cohort. Although the frailty index was linked to the risk of death in both cohorts, the hazards ratio decreased from 1.67 per 0.1 increment in the frailty index for the first cohort to 1.32 for the second cohort (interaction term p = .005). DISCUSSION: Although frailty was as common at age 70 as before, its lethality appears to be less. Just why this is so should be explored further.
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