ArticleJournal of psychosomatic research2016
Medical comorbidity and distress in patients with irritable bowel syndrome: The moderating role of age.
Article in Journal of psychosomatic research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Psychopathological and neuropsychological disorders associated with chronic primary visceral pain: Systematic review.Frontiers in psychology · 2022Pooled it
- Screening for irritable bowel syndrome and its associated factors among patients with type 2 diabetes mellitus attending outpatient clinics in Jeddah, Saudi Arabia: A cross-sectional study.Journal of family medicine and primary care · 2026Article
- Mirtazapine for gastrointestinal and neuropsychological symptoms in older adults with irritable bowel syndrome.Therapeutic advances in gastroenterology · 2024Review
- Emotional distress and multimorbidity patterns in Chinese Han patients with osteoporosis: a network analysis.Frontiers in public health · 2023Article
- Irritable bowel syndrome in adults: Prevalence and risk factors.Annals of medicine and surgery (2012) · 2022Article
- Abdominal Pain Severity Is Mainly Associated with Bloating Severity in Patients with Functional Bowel Disorders and Functional Abdominal Pain.Digestive diseases and sciences · 2022Article
- Research on Correlation Between Psychological Factors, Mast Cells, and PAR-2 Signal Pathway in Irritable Bowel syndrome.Journal of inflammation research · 2021Article
- Psychological distress among mountainous farmers in Vietnam: a cross-sectional study of prevalence and associated factors.BMJ open · 2020Article
- Examining the Role of Anxiety and Depression in Dietary Choices among College Students.Nutrients · 2020Article
- A Machine Learning Approach for Studying the Comorbidities of Complex Diagnoses.Behavioral sciences (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesIrritable bowel syndrome (IBS) affects people across the age spectrum and is highly comorbid with other medical conditions. The aim of this study was to determine the moderating effect of age on the relationship between medical comorbidity and health outcomes in IBS patients.
methodsPatients (n=384) across the age spectrum (18 to 70) completed questionnaires regarding medical comorbidities, anxiety, depression, IBS symptom severity, and IBS quality of life (QOL).
resultsThe mean age was 41 (SD=15). Age interacted with medical comorbidities to predict anxiety, F(7,354)=5.82, p=0.009, R(2)=0.10. Results revealed significant main effects for education, β=-0.16, p<0.05, age, β=-0.15, p<0.05, medical comorbidities, β=0.25, p<0.05, and a significant interaction, β=-0.15, p<0.01. Anxiety was greater among patients with many comorbidities, with this effect being more pronounced for younger adults. Depression, also predicted by the interaction between age and comorbidities, showed the same pattern as anxiety. There was no significant interaction between age and medical comorbidities in predicting IBS symptom severity or IBS QOL.
conclusionDistress among IBS patients with medical comorbidities varies with age, with higher levels of anxiety and depression among younger adults than their older counterparts. Medical comorbidity may have a more selective impact on psychological distress as compared to IBS symptom severity and quality of life for younger adults with IBS. Distress may increase IBS burden for these patients and complicate its medical management.
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