Evidence map›Paper›PMID 27519893›Full record

ArticleJournal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology2007

Spontaneous bilateral Achilles tendon rupture in a patient treated with oral levofloxacin.

A E Salvi, G P Metelli, A Bosco, A Berizzi, S A Hacking, A Cantalamessa

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In one paragraph

Article in Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

A E SalviOrthopaedics and Traumatology Department, Mellino Mellini Hospital Trust Civil Hospital of Iseo, I-25049, Iseo (BS), Italy. andrea@orthopaedics.com.
G P MetelliOrthopaedics and Traumatology Department, Mellino Mellini Hospital Trust Civil Hospital of Iseo, I-25049, Iseo (BS), Italy.
A BoscoAccident and Emergency Department Mellino Mellini Hospital Trust, Civil Hospital of Iseo, Iseo (BS), Italy.
A BerizziOrthopaedics and Traumatology Department, University of Padua, Padua, Italy.
S A HackingDepartment of Orthopaedics JTN Wong Labs for Mineralized Tissue Research, McGill University, Montreal, Quebec, Canada.
A CantalamessaDepartment of Internal Medicine Mellino Mellini Hospital Trust, Civil Hospital of Iseo, Iseo (BS), Italy.
CTO Hospital · ITMcGill University · CAUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A case of bilateral rupture of the Achilles tendon in a patient treated with levofloxacin for cystitis is reported. A 76-year-old woman suddenly developed painful ankles one day after levofloxacin treatment. Drug therapy was switched to amoxicillin/clavulanate on the fourth day. Sonography revealed a serious condition of tendinosis with complete bilateral full-thickness rupture on day 6. Tendons were both repaired in the same surgical session. Pathological anatomy of the specimens reported fatty tissue lobules with panniculitis and histiocytosis. Ankles were immobilized postoperatively with a plaster cast. Achilles tendon rupture may occur as an adverse side effect of short-term use of levofloxacin, a fluoroquinolone antibiotic. This adverse effect is a rare and poorly understood complication of this antibiotic therapy. A review of the literature is provided.

Indexed as

Achilles tendonAntibioticCystitisFluoroquinoloneLevofloxacinTendinosisTendon rupture

Identifiers

PMID27519893
PMCPMC4484540
OpenAlexW2082553650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.