ArticleCardiovascular diabetology2016
High levels of serum vitamin D are associated with a decreased risk of metabolic diseases in both men and women, but an increased risk for coronary artery calcification in Korean men.
Article in Cardiovascular diabetology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- VDR Gene variation and insulin resistance related diseases.Lipids in health and disease · 2017Pooled it
- The Paradox of Physical Activity and Coronary Artery Calcification: Implications for Cardiovascular Risk.Journal of clinical medicine · 2024Review
- Osteoporosis and vascular calcifications.Endocrine connections · 2023Review
- Vitamin D in atherosclerosis and cardiovascular events.European heart journal · 2023Review
- Serum biomarkers for arterial calcification in humans: A systematic review.Bone reports · 2022Review
- Vitamin D insufficiency is associated with inflammation and deregulation of adipokines in patients with metabolic syndrome.BMC endocrine disorders · 2022Article
- Association between circulating 25-hydroxyvitamin D and cardiometabolic risk factors in adults in rural and urban settings.Nutrition & diabetes · 2022Article
- The Biological Role of Vitamins in Athletes' Muscle, Heart and Microbiota.International journal of environmental research and public health · 2022Review
- Monocyte-to-HDL Ratio (MHR) Predicts Vitamin D Deficiency in Healthy and Metabolic Women: A Cross-Sectional Study in 1048 Subjects.Nutrients · 2022Article
- Vitamin D and Its Metabolites Deficiency in Acute Coronary Syndrome Patients Undergoing Coronary Angiography: A Case-Control Study.Vascular health and risk management · 2021Article
- Inadequacy of Vitamin D Nutritional Status in Individuals with Metabolically Unhealthy Obesity Phenotype: The Relevance of Insulin Resistance.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Vitamin D deficiency and metabolic syndrome in elderly Chinese individuals: evidence from CLHLS.Nutrition & metabolism · 2020Article
- Interactive and Multifactorial Mechanisms of Calcific Vascular and Valvular Disease.Trends in endocrinology and metabolism: TEM · 2019Review
- Evaluation of the impact of glycemic status on the progression of coronary artery calcification in asymptomatic individuals.Cardiovascular diabetology · 2018Article
- Fat-soluble micronutrients and metabolic syndrome.Current opinion in clinical nutrition and metabolic care · 2017Review
- Gender differences in hospital admissions for major cardiovascular events and procedures in people with and without diabetes in England: a nationwide study 2004-2014.Cardiovascular diabetology · 2017Article
- Evaluation of vitamin D levels in relation to coronary CT angiographic findings in an Iranian population.Vascular health and risk management · 2017Article
- Displacement of Surgical Clips during Postoperative Radiotherapy in Breast Cancer Patients Who Received Breast-Conserving Surgery.Journal of breast cancer · 2016Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are conflicting results for relationships between serum vitamin D levels and metabolic diseases. The aim of this study was to investigate whether serum vitamin D levels were associated with various metabolic diseases including insulin resistance (IR), metabolic syndrome (MS), fatty liver (FL), and coronary artery calcification (CAC), along with assessing gender differences for these relationships in Korean adults.
methodsA total of 180,918 subjects (98,412 men and 82,506 women) who participated in a comprehensive health examination in the 2012-2013 period at Kangbuk Samsung Hospital, College of Medicine, Sungkyunkwan University were included. Serum vitamin D and metabolic markers were analyzed and CAC was estimated. Subjects were divided according to quartile groups of serum vitamin D. To examine the relationships of serum vitamin D to metabolic diseases and metabolic factors, multivariate logistic analysis was conducted.
resultsHigh levels of serum vitamin D was associated with lower ORs for MS, IR and FL both in men and women (all p < 0.05). For men, ORs for CAC were significantly higher in third and the highest quartile groups for serum vitamin D in all the analyzed models (all p < 0.05). However, women showed no significant results between serum vitamin D and CAC.
conclusionsHigh levels of serum vitamin D were associated with lower risk of MS, IR and FL in both Korean men and women, but were associated with higher risk of CAC only in men, and not in women.
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