Evidence map›Paper›PMID 27519543›Full record

ArticlePhysiological genomics2016

Differential roles of caveolin-1 in ouabain-induced Na+/K+-ATPase cardiac signaling and contractility.

Yan Bai, Jian Wu, Daxiang Li, Eric E Morgan, Jiang Liu, Xiaochen Zhao, Aaron Walsh, Jagannath Saikumar, Jodi Tinkel, Bina Joe and 2 more

Abstract read
In one paragraph

Article in Physiological genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. The Redox-Sensitive Na/K-ATPase Signaling in Uremic Cardiomyopathy.International journal of molecular sciences · 2020
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Na⁺Molecules (Basel, Switzerland) · 2017
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Yan BaiDepartment of Biochemistry and Cancer Biology, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio; Pediatrics Department of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, HuBei, China.
Jian WuDepartment of Biochemistry and Cancer Biology, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio.
Daxiang LiDepartment of Biochemistry and Cancer Biology, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio; State Key Laboratory of Tea Plant Biology and Utilization, Anhui Agricultural University, Hefei, Anhui, China; and.
Eric E MorganCenter for Hypertension and Personalized Medicine, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio.
Jiang LiuDepartment of Pharmacology, Physiology and Toxicology, JCE School of Medicine, Marshall University, Huntington, West Virginia.
Xiaochen ZhaoDepartment of Physiology and Pharmacology, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio.
Aaron WalshDepartment of Biochemistry and Cancer Biology, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio.
Jagannath SaikumarDepartment of Physiology and Pharmacology, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio.
Jodi TinkelDepartment of Medicine, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio.
Bina JoeDepartment of Physiology and Pharmacology, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio; Center for Hypertension and Personalized Medicine, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio.
Rajesh GuptaDepartment of Medicine, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio.
Lijun LiuDepartment of Biochemistry and Cancer Biology, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio; Department of Medicine, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio; Center for Hypertension and Personalized Medicine, College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio; Lijun.liu@utoledo.edu.
University of Toledo · USMarshall University · US

Funding

STRUCTURE/FUNCTION RELATIONSHIPS OF OUBAIN SENSITIVE ION PUMPSP01HL036573 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI ASKARI, AMIR · 1986 to 2013
$16.4M
Genetics of HypertensionR01HL020176 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI JOE, BINA · 1985 to 2017
$8.1M
NHLBI NIH HHS P01 HL036573NHLBI NIH HHS R01 HL020176
6 · The paper itself

Abstract

Binding of ouabain to cardiac Na

Indexed as

AnimalsCaveolin 1CholesterolFibroblastsMaleMAP Kinase Signaling SystemMiceMice, KnockoutMyocardial ContractionMyocytes, CardiacOuabainPhosphatidylinositol 3-KinasesSignal TransductionSodium-Potassium-Exchanging ATPaseCav1 protein, mouseCaveolin 1CholesterolOuabainPhosphatidylinositol 3-KinasesSodium-Potassium-Exchanging ATPasecaveolin-1contractilityNa+/K+-ATPaseouabainsignaling

Identifiers

PMID27519543
PMCPMC5243228
OpenAlexW2516983412

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.