Evidence map›Paper›PMID 27518377›Full record

ArticleCritical care medicine2016

Cost Associated With Pediatric Delirium in the ICU.

Chani Traube, Elizabeth A Mauer, Linda M Gerber, Savneet Kaur, Christine Joyce, Abigail Kerson, Charlene Carlo, Daniel Notterman, Stefan Worgall, Gabrielle Silver and 1 more

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Critical care medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 60 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 4 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03572257 phase2 / phase3withdrawnnot on this mapstarted 2019, after this paper: background citation

Prospective, Double-Blind, Randomized Controlled Trial of Quetiapine as a Treatment for Delirium in Critically Ill Children

TypeinterventionalSponsorMedical College of WisconsinRan2019 to 2020Enrolled0ConditionsDeliriumArmsQuetiapine, Placebo
NCT07365215 completednot on this mapstarted 2023, after this paper: background citation

Pediatric Delirium in Swedish PICUs: Incidence, Risk Factors, and Validation of the Swedish Cornell Assessment of Pediatric Delirium (CAPD) Instrument.

Typeobservational_patient_registrySponsorUppsala UniversityRan2023 to 2025Enrolled676ConditionsPediatric Delirium, Pediatric Intensive Care, Risk Factors
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 4 syntheses or guidelines pooled it, 182 citations in OpenAlex.

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  15. Delirium in the NICU.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Chani Traube1Pediatric Critical Care Medicine, Weill Cornell Medical College, New York, NY.2Department of Healthcare Policy and Research, Weill Cornell Medical College, New York, NY.3Weill Cornell Medical College, New York, NY.4Department of Molecular Biology, Princeton University, Princeton, NJ.5Department of Pediatrics, Weill Cornell Medical College, New York, NY.6Department of Child Psychiatry, Weill Cornell Medical College, New York, NY.
Elizabeth A Mauer
Linda M Gerber
Savneet Kaur
Christine Joyce
Abigail Kerson
Charlene Carlo
Daniel Notterman
Stefan Worgall
Gabrielle Silver
Bruce M Greenwald
Cornell University · USPrinceton University · US

Funding

Clinical and Translational Science CenterUL1TR000457 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2012 to 2016
$46.0M
Scientific and Technical Computing CoreP2CHD047879 · NICHD · PRINCETON UNIVERSITY · PI SALGANIK, MATTHEW J. · 2014 to 2018
$2.0M
NCATS NIH HHS UL1 TR000457NICHD NIH HHS P2C HD047879
6 · The paper itself

Abstract

objectiveTo determine the costs associated with delirium in critically ill children.

designProspective observational study.

settingAn urban, academic, tertiary-care PICU in New York city. PATIENTS: Four-hundred and sixty-four consecutive PICU admissions between September 2, 2014, and December 12, 2014.

interventionsNone. MEASUREMENTS AND MAIN

resultsAll children were assessed for delirium daily throughout their PICU stay. Hospital costs were analyzed using cost-to-charge ratios, in 2014 dollars. Median total PICU costs were higher in patients with delirium than in patients who were never delirious ($18,832 vs $4,803; p < 0.0001). Costs increased incrementally with number of days spent delirious (median cost of $9,173 for 1 d with delirium, $19,682 for 2-3 d with delirium, and $75,833 for > 3 d with delirium; p < 0.0001); this remained highly significant even after adjusting for PICU length of stay (p < 0.0001). After controlling for age, gender, severity of illness, and PICU length of stay, delirium was associated with an 85% increase in PICU costs (p < 0.0001).

conclusionsPediatric delirium is associated with a major increase in PICU costs. Further research directed at prevention and treatment of pediatric delirium is essential to improve outcomes in this population and could lead to substantial healthcare savings.

Indexed as

AdolescentChildChild, PreschoolDeliriumFemaleHospital CostsHumansInfantInfant, NewbornIntensive Care Units, PediatricMaleProspective Studies

Identifiers

PMID27518377
PMCPMC5592112
OpenAlexW2514395058

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.