Evidence map›Paper›PMID 27517943›Full record

ArticleInternational journal of environmental research and public health2016

Association between Exposure to Endocrine Disruptors in Drinking Water and Preterm Birth, Taking Neighborhood Deprivation into Account: A Historic Cohort Study.

Marion Albouy-Llaty, Frédérike Limousi, Camille Carles, Antoine Dupuis, Sylvie Rabouan, Virginie Migeot

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Drinking Water Contaminant Concentrations and Birth Outcomes.Journal of policy analysis and management : [the journal of the Association for Public Policy Analysis and Management] · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Pesticides and Child's Health in France.Current environmental health reports · 2018
    Review
  12. Article
  13. Drinking Water Nitrate and Human Health: An Updated Review.International journal of environmental research and public health · 2018
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Marion Albouy-LlatyDepartment of Analytical Chemistry, Pharmaceutics and Epidemiology, School of Medicine and Pharmacy, University of Poitiers, 6 rue de la Milétrie, 86034 Poitiers Cedex, France. marion.albouy-llaty@chu-poitiers.fr.
Frédérike LimousiDepartment of Analytical Chemistry, Pharmaceutics and Epidemiology, School of Medicine and Pharmacy, University of Poitiers, 6 rue de la Milétrie, 86034 Poitiers Cedex, France. frederike.limousi@gmail.com.
Camille CarlesEpidemiology of Cancer and Environmental Exposures, Inserm U1219, University of Bordeaux, 146 rue Léo Saignat, 33076 Bordeaux, France. Camille.Carles@isped.u-bordeaux2.fr.
Antoine DupuisDepartment of Analytical Chemistry, Pharmaceutics and Epidemiology, School of Medicine and Pharmacy, University of Poitiers, 6 rue de la Milétrie, 86034 Poitiers Cedex, France. antoine.dupuis@univ-poitiers.fr.
Sylvie RabouanDepartment of Analytical Chemistry, Pharmaceutics and Epidemiology, School of Medicine and Pharmacy, University of Poitiers, 6 rue de la Milétrie, 86034 Poitiers Cedex, France. sylvie.rabouan@univ-poitiers.fr.
Virginie MigeotDepartment of Analytical Chemistry, Pharmaceutics and Epidemiology, School of Medicine and Pharmacy, University of Poitiers, 6 rue de la Milétrie, 86034 Poitiers Cedex, France. virginie.migeot@univ-poitiers.fr.
Inserm · FRUniversité de Bordeaux · FRUniversité de Poitiers · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between preterm birth (PTB) and endocrine disruptor exposure in drinking-water has only occasionally been studied. The objective of this work was to investigate the relation between exposure to atrazine metabolites, or atrazine/nitrate mixtures, in drinking-water during pregnancy and prevalence of PTB neonates, while taking neighborhood deprivation into account.

methodA historic cohort study in Deux-Sèvres, France, between 2005 and 2010 with a multiple imputation model for data of exposure to atrazine metabolites and a logistic regression were carried out.

resultsWe included 13,654 mother/neonate pairs living in 279 different census districts. The prevalence of PTB was 4%. Average atrazine metabolite concentration was 0.019 ± 0.009 (0.014-0.080) µg/L and 39% of mothers lived in less deprived areas. The individual data were associated with risk of PTB. The risk of PTB when exposed to highest concentration of atrazine metabolite adjusted for confounders, was ORa 1.625 95% CI [0.975; 2.710]. Taking, or not, neighborhood deprivation into account did not change the result. Exposure to atrazine/nitrate mixtures remained non-significant.

conclusionsEven if we took neighborhood deprivation into account, we could not show a significant relationship between exposure to atrazine metabolites, or mixtures, in drinking-water during the second trimester of pregnancy and PTB.

Indexed as

Poverty AreasResidence CharacteristicsAdultAtrazineCohort StudiesDrinking WaterEndocrine DisruptorsFemaleFranceHumansInfant, NewbornLogistic ModelsNitratesPregnancyPremature BirthPrevalenceAtrazineDrinking WaterEndocrine DisruptorsNitratesdrinking-waterendocrine disruptorEuropean deprivation indexmixturepreterm birthsocial inequalities

Identifiers

PMID27517943
PMCPMC4997482
OpenAlexW2511558935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.