Evidence map›Paper›PMID 27517913›Full record

ReviewInternational journal of molecular sciences2016

Towards Effective Photothermal/Photodynamic Treatment Using Plasmonic Gold Nanoparticles.

Alla Bucharskaya, Galina Maslyakova, Georgy Terentyuk, Alexander Yakunin, Yuri Avetisyan, Olga Bibikova, Elena Tuchina, Boris Khlebtsov, Nikolai Khlebtsov, Valery Tuchin

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 140 citations in OpenAlex.

  1. Review
  2. Review
  3. Shifting cold to hot tumors by nanoparticle-loaded drugs and products.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Nano-biotechnology in tumour and cancerous disease: A perspective review.Journal of cellular and molecular medicine · 2023
    Review
  8. Article
  9. Review
  10. Review
  11. Combination of [Pharmaceutics · 2022
    Article
  12. Review
  13. Lasers in Live Cell Microscopy.International journal of molecular sciences · 2022
    Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Nanotechnology against COVID-19: Immunization, diagnostic and therapeutic studies.Journal of controlled release : official journal of the Controlled Release Society · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Alla BucharskayaResearch Institute for Fundamental and Clinical Uronephrology, Saratov State Medical University, n.a. V.I. Razumovsky, 410012 Saratov, Russia. Alla_alla72@mail.ru.
Galina MaslyakovaResearch Institute for Fundamental and Clinical Uronephrology, Saratov State Medical University, n.a. V.I. Razumovsky, 410012 Saratov, Russia. gmaslyakova@yandex.ru.
Georgy TerentyukResearch Institute for Fundamental and Clinical Uronephrology, Saratov State Medical University, n.a. V.I. Razumovsky, 410012 Saratov, Russia. vetklinikanew@mail.ru.
Alexander YakuninInstitute of Precision Mechanics and Control, RAS, 410028 Saratov, Russia. anyakunin@mail.ru.
Yuri AvetisyanInstitute of Precision Mechanics and Control, RAS, 410028 Saratov, Russia. yuaavetisyan@mail.ru.
Olga BibikovaResearch-Education Institute of Optics and Biophotonics, Saratov National Research State University, 410012 Saratov, Russia. olyabibikova@gmail.com.
Elena TuchinaDepartment of Biology, Saratov National Research State University, 410012 Saratov, Russia. firstflower@yandex.ru.
Boris KhlebtsovInstitute of Biochemistry and Physiology of Plants and Microorganisms, RAS, 410049 Saratov, Russia. khlebtsov_b@ibppm.ru.
Nikolai KhlebtsovInstitute of Biochemistry and Physiology of Plants and Microorganisms, RAS, 410049 Saratov, Russia. khlebtsov@ibppm.ru.
Valery TuchinResearch-Education Institute of Optics and Biophotonics, Saratov National Research State University, 410012 Saratov, Russia. tuchinvv@mail.ru.
Saratov State University · RUInstitute of Precision Mechanics and Control · RUSaratov State Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gold nanoparticles (AuNPs) of different size and shape are widely used as photosensitizers for cancer diagnostics and plasmonic photothermal (PPT)/photodynamic (PDT) therapy, as nanocarriers for drug delivery and laser-mediated pathogen killing, even the underlying mechanisms of treatment effects remain poorly understood. There is a need in analyzing and improving the ways to increase accumulation of AuNP in tumors and other crucial steps in interaction of AuNPs with laser light and tissues. In this review, we summarize our recent theoretical, experimental, and pre-clinical results on light activated interaction of AuNPs with tissues and cells. Specifically, we discuss a combined PPT/PDT treatment of tumors and killing of pathogen bacteria with gold-based nanocomposites and atomic clusters, cell optoporation, and theoretical simulations of nanoparticle-mediated laser heating of tissues and cells.

Indexed as

GoldMetal NanoparticlesNanotubesPhotochemotherapySilicon DioxideGoldSilicon DioxideAu nanoparticlescell optoporationnanocompositesnanorodsnanostarspathogensphotodynamic therapy (PDT)photothermal therapy (PPT)silicatumors

Identifiers

PMID27517913
PMCPMC5000692
OpenAlexW2512062905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.