Evidence map›Paper›PMID 27517544›Full record

SynthesisEuropean journal of nutrition2017

Cheese consumption and risk of cardiovascular disease: a meta-analysis of prospective studies.

Guo-Chong Chen, Yan Wang, Xing Tong, Ignatius M Y Szeto, Gerrit Smit, Zeng-Ning Li, Li-Qiang Qin

Erratum issuedAbstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in European journal of nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 43 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 13 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. European guidance for the diagnosis and management of osteoporosis in postmenopausal women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Guideline
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Pooled it
  14. Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Guo-Chong ChenDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, 199 Renai Road, 215123, Suzhou, China.
Yan WangYili Innovation Center, Inner Mongolia Yili Industrial Group Co., Ltd., Hohhot, China.
Xing TongDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, 199 Renai Road, 215123, Suzhou, China.
Ignatius M Y SzetoYili Innovation Center, Inner Mongolia Yili Industrial Group Co., Ltd., Hohhot, China.
Gerrit SmitYili R&D Center, 6708 PB, Wageningen, The Netherlands.
Zeng-Ning LiDepartment of Nutrition, The First Hospital of Hebei Medical University, 050031, Shijiazhuang, China.
Li-Qiang QinDepartment of Nutrition and Food Hygiene, School of Public Health, Soochow University, 199 Renai Road, 215123, Suzhou, China. qinliqiang@suda.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCheese contains a high content of saturated fatty acids but also lists of potentially beneficial nutrients. How long-term cheese consumption affects the development of cardiovascular disease (CVD) is unclear. A meta-analysis of prospective observational studies was conducted to evaluate the risks of total CVD, coronary heart disease (CHD), and stroke associated with cheese consumption.

methodsPotentially eligible studies were identified by searching PubMed and EMBASE databases and by carefully reviewing the bibliographies of retrieved publications and related reviews. The summary relative risks (RRs) with 95 % confidence intervals (CIs) were calculated using the random-effects model.

resultsThe final analyses included 15 prospective studies. Most of the studies excluded prevalent CVD at baseline (14/15) and had a duration >10 years (13/15). The summary RR for high vs. low cheese consumption was 0.90 (95 % CI 0.82-0.99) for total CVD (7 studies, 8076 events), 0.86 (95 % CI 0.77-0.96) for CHD (8 studies, 7631 events), and 0.90 (95 % CI 0.84-0.97) for stroke (7 studies, 10,449 events), respectively. The restricted cubic model indicated evidence of nonlinear relationships between cheese consumption and risks of total CVD (P

conclusionsThis meta-analysis of prospective studies suggests a nonlinear inverse association between cheese consumption and risk of CVD.

Indexed as

CheeseCardiovascular DiseasesDietHumansObservational Studies as TopicRisk FactorsSensitivity and SpecificityCardiovascular diseaseCheeseDairyMeta-analysis

Identifiers

PMID27517544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.