ReviewCurrent opinion in obstetrics & gynecology2016
What's new in the functional anatomy of pelvic organ prolapse?
Review in Current opinion in obstetrics & gynecology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 4 syntheses or guidelines pooled it, 156 citations in OpenAlex.
- Diffusion tensor imaging of the pelvic floor muscles and pelvic organs: a systematic review.Frontiers in medical technology · 2026Pooled it
- Type III Collagen RNA Level Expression in Pelvic Organ Prolapse: A Systematic Review and Meta-Analysis.International urogynecology journal · 2024Pooled it
- Self-care of vaginal pessary for pelvic organ prolapse: a systematic review and meta-analysis.Archives of gynecology and obstetrics · 2024Pooled it
- Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank.Communications biology · 2020Pooled it
- Autonomic Plexuses of the Female Sexual Organs Travel Within Pubocervical and Rectovaginal [Endopelvic] Fascia: A Rationale for 'Nerve-Aware' Vaginal Prolapse Repair.Clinical anatomy (New York, N.Y.) · 2026Article
- Focused Training in Pelvic Floor Surgery: A CUSUM Analysis of the Learning Curve in Uterosacral Ligament Suspension.Healthcare (Basel, Switzerland) · 2026Article
- The Immediate Impact of Heavy Weightlifting on Pelvic Floor Morphometry in Vaginally Parous Women: A Repeated Measures Study.International urogynecology journal · 2026Article
- Compartment-Specific Associations Between Perineal Body Length and Pelvic Organ Prolapse in Postpartum Women.International urogynecology journal · 2026Article
- 3D MRI Biomarkers for Predicting Pelvic Organ Prolapse Risk and Severity.International urogynecology journal · 2026Article
- Large language models in systematic review and meta-analysis of surgical treatments for vaginal vault prolapse.NPJ digital medicine · 2026Article
- Bony birth canal and pelvic organ prolapse: a quantitative assessment for dimensions of pelvic midplanes based on MRI.Abdominal radiology (New York) · 2025Article
- Assessing Postpartum Levator Ani Muscle Recovery: A Feasibility Study on Automated Texture Analysis in Transvaginal Ultrasound.Ultrasound in medicine & biology · 2025Article
- Pelvic Floor Dysfunction in the Transgender Patient: A Scoping Review.International urogynecology journal · 2025Article
- The Pull-Out Strength of Laparoscopic Sacrohysteropexy and Vaginal Sacrospinous Ligament Fixation in a Cadaver Model.International urogynecology journal · 2025Article
- To Study the Effectiveness of Using Suture Passer in Sacrospinous Vault Fixation Surgery.Journal of pharmacy & bioallied sciences · 2025Article
- High and low take-off external prolapse phenotypes can be characterised preoperatively on defaecation proctography.Techniques in coloproctology · 2025Article
- Voiding urodynamics parameters for women with and without symptomatic pelvic organ prolapse.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Article
- Long-Term Self-Management of Vaginal Cube Pessaries Can Improve Sexual Life in Patients with Pelvic Organ Prolapse, Results from a Secondary Analysis.International urogynecology journal · 2024Article
- Anterior Colporrhaphy and Paravaginal Repair for Anterior Compartment Prolapse: A Review.Medicina (Kaunas, Lithuania) · 2024Review
- Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
purpose of reviewProvide an evidence-based review of pelvic floor functional anatomy related to pelvic organ prolapse. RECENT
findingsPelvic organ support depends on interactions between the levator ani muscle and pelvic connective tissues. Muscle failure exposes the vaginal wall to a pressure differential producing abnormal tension on the attachments of the pelvic organs to the pelvic sidewall. Birth-induced injury to the pubococcygeal portion of the levator ani muscle is seen in 55% of women with prolapse and 16% of women with normal support. Failure of the lateral connective tissue attachments between the uterus and vagina to the pelvic wall (cardinal, uterosacral, and paravaginal) are strongly related with prolapse (effect sizes ∼2.5) and are also highly correlated with one another (r ∼ 0.85). Small differences exist with prolapse in factors involving the vaginal wall length and width (effect sizes ∼1). The primary difference in ligament properties between women with and without prolapse is found in ligament length. Only minor differences in ligament stiffness are seen. SUMMARY: Pelvic organ prolapse occurs because of injury to the levator ani muscles and failure of the lateral connections between the pelvic organs to the pelvic sidewall. Abnormalities of the vaginal wall fascial tissues may play a minor role.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.