Evidence map›Paper›PMID 27517038›Full record

ReviewFrontiers in cardiovascular medicine2016

Venous Thromboembolism in Cancer: An Update of Treatment and Prevention in the Era of Newer Anticoagulants.

Waqas Qureshi, Zeeshan Ali, Waseem Amjad, Zaid Alirhayim, Hina Farooq, Shayan Qadir, Fatima Khalid, Mouaz H Al-Mallah

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Successful Treatment of Recurrent Thrombosis Associated with Malignancy with Apixaban and Follow-up for 1 Year.The International journal of angiology : official publication of the International College of Angiology, Inc · 2020
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Acute lymphoblastic leukemia presenting with mesenteric ischemia.Gastroenterology and hepatology from bed to bench · 2019
    Article
  14. Observational
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

Waqas QureshiDepartment of Internal Medicine, Division of Cardiovascular Epidemiology and Cardiology, Wake Forest University , Winston Salem, NC , USA.
Zeeshan AliDepartment of Internal Medicine, University of Maryland , Baltimore, MD , USA.
Waseem AmjadAllama Iqbal Medical College , Lahore , Pakistan.
Zaid AlirhayimDepartment of Internal Medicine, Henry Ford Hospital, Wayne State University , Detroit, MI , USA.
Hina FarooqRawalpindi Medical College , Rawalpindi , Pakistan.
Shayan QadirKhyber Medical College , Peshawar , Pakistan.
Fatima KhalidDepartment of Internal Medicine, Division of Nephrology and Hypertension, Wake Forest University , Winston Salem, NC , USA.
Mouaz H Al-MallahKing Abdulaziz Medical Center , Riyadh , Saudi Arabia.
Wake Forest University · USAllama Iqbal Medical College · PKHenry Ford Hospital · USKhyber Medical College · PKKing Abdulaziz Medical City · SARawalpindi Medical University · PKUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer patients are at major risk of developing venous thromboembolism (VTE), resulting in increased morbidity and economic burden. While a number of theories try to explain its pathophysiology, its risk stratification can be broadly done in cancer-related, treatment-related, and patient-related factors. Studies report the prophylactic use of thrombolytic agents to be safe and effective in decreasing VTE-related mortality/morbidity especially in postoperative cancer patients. Recent data also suggest the prophylactic use of low molecular weight Heparins (LMWHs) and Warfarin to be effective in reducing VTEs related to long-term central venous catheter use. In a double-blind, multicenter trial, a new ultra-LMWH Semuloparin has shown to be efficacious in preventing chemotherapy-associated VTE's along with other drugs, such as Certoparin and Nadoparin. LMWHs are reported to be very useful in preventing recurrent VTEs in advanced cancers and should be preferred over full dose Warfarin. However, their long-term safety beyond 6 months has not been established yet. Furthermore, this paper discusses the safety and efficacy of different drugs used in the treatment and prevention of recurrent VTEs, including Bemiparin, Semuloparin, oral direct thrombin inhibitors, parenteral and direct oral factor Xa inhibitors.

Indexed as

apixabanlow molecular weight heparinnewer oral anticoagulantsrisk stratificationrivaroxabanthromboprophylaxisvenous thromboembolism

Identifiers

PMID27517038
PMCPMC4963402
OpenAlexW2494049461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.