ArticleAvicenna journal of phytomedicine
In vitro protoscolicidal effects of various concentrations of Ziziphora tenuior L. extract at different exposure times.
Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Comparison of the Scolicidal Activity of Two Leaves Extracts of Myrtus communis from Algeria Against Echinococcus granulosus Sensu Lato Protoscoleces.Acta parasitologica · 2024Article
- Histopathological Study to Evaluate the Effect of Aqueous Extract ofArchives of Razi Institute · 2023Article
- Epidemiological study ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2018Article
- Cystic echinococcosis: A neglected disease at usual and unusual locations.Tropical parasitologyArticle
- The physiological and pharmacological effects ofAvicenna journal of phytomedicineReview
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Authors and funding
6 authors.
Funding
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Abstract
objectiveHydatidosis is one of the most important zoonotic diseases and surgery is still the main treatment for this problem. One of the side effects of hydatid cyst surgery is recurrence, thus, searching and assessment of some new agents such as medicinal plant extracts are very important. In the present study, the scolicidal effect of ethanolic extract of Ziziphora tenuior (Z. tenuior) was investigated. MATERIALS AND
methodsProtoscolices were aseptically collected from sheep livers containing hydatid cyst and used in the experiments. Z. tenuior extract was used at concentration of 3-100 mg/ml for 10-60 min. Viability of protoscolices was determined by 0.1% eosin staining.
resultsBased on our results, Z. tenuior extract at concentration of 10 mg/ml killed all protoscolices after 20 min. However, this medicinal plant at concentration of 25 mg/ml destroyed all protoscolices in a shorter exposure time (10 min). Therefore, the scolicidal activity of the extract at 10 and 25 mg/ml concentrations was considerably effective in lower concentrations and shorter exposure times.
conclusionThe findings of this study showed that the ethanolic extract of Z. tenuior produces high scolicidal activity; it may be used as an appropriate and effective scolicidal agent in hydatidosis surgery. This is the first report on the protoscolicidal activity of Z. tenuior.
Indexed as
Identifiers
27516978PMC4967833What OpenQuestion holds
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