ArticleSpringerPlus2016
Associations between adherence, depressive symptoms and health-related quality of life in young adults with cystic fibrosis.
Article in SpringerPlus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evolution of body image across treatment eras: a systematic review in young people and adults living with cystic fibrosis.European respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- The Impact of Personal-Level Social Networks on Treatment Adherence, Depression, Anxiety, and Perceived Stigma Among Adults with Cystic Fibrosis: An Egocentric Network Analysis.International journal of behavioral medicine · 2026Article
- What are the symptoms and concerns of young adults living with life-limiting conditions and how well are they captured by patient reported outcome measures? A mixed-methods systematic review and framework synthesis.Palliative medicine · 2026Review
- Association of depressive symptoms with sweat chloride variability and medication possession ratio during long-term Elexacaftor/Tezacaftor/Ivacaftor therapy in adolescents and young adults with cystic fibrosis.Frontiers in pediatrics · 2026Article
- Anxiety, depression, physical disease parameters and health-related quality of life in the BronchUK national bronchiectasis cohort.ERJ open research · 2025Article
- A call to action [plans] for cyclic vomiting syndrome.Neurogastroenterology and motility · 2025Review
- Predictive role of spiritual health, resilience, and mental well-being in treatment adherence among hemodialysis patients.BMC nephrology · 2024Article
- Assessing the health impacts of parenthood on people with cystic fibrosis: the HOPeCF prospective cohort protocol.BMJ open respiratory research · 2024Observational
- Racial inequities and rareJournal of clinical & translational endocrinology · 2024Article
- Effect of elevated depressive symptoms during adolescence on health-related quality of life in young adulthood-a six-year cohort study with repeated exposure measurements.Frontiers in pediatrics · 2024Article
- Self-Reported Medication Adherence Measured with Morisky Scales in Rare Disease Patients: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2023Review
- Work participation in adults with rare genetic diseases - a scoping review.BMC public health · 2023Article
- Rounding out the pediatric CF care team: Including the profession of occupational therapy.Pediatric pulmonology · 2023Article
- Use of inhaled antibiotics among Danish patients with cystic fibrosis.Pediatric pulmonology · 2022Article
- Exploring Associations Between Self-Compassion, Self-Criticism, Mental Health, and Quality of Life in Adults with Cystic Fibrosis: Informing Future Interventions.Journal of clinical psychology in medical settings · 2022Article
- Introducing a MAP for adherence care in the paediatric cystic fibrosis clinic: a multiple methods implementation study.BMC health services research · 2022Article
- Anxiety and depression in Dutch patients with primary ciliary dyskinesia and their caregivers: associations with health-related quality of life.ERJ open research · 2021Article
- Association between Psychiatric Disorders and Glomerular Disease.Glomerular diseases · 2021Article
- Global Burden of Anxiety and Depression among Cystic Fibrosis Patient: Systematic Review and Meta-Analysis.International journal of chronic diseases · 2021Review
- Influence of Cystic Fibrosis-Related Diabetes on Mental Health in Adults: A Single-Center Study.Lung · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCystic fibrosis (CF) is a life shortening disease, however prognosis has improved and the adult population is growing. Most adults with cystic fibrosis live independent lives and balance the demands of work and family life with a significant treatment burden. The aim of this study was to examine the relationships among treatment adherence, symptoms of depression and health-related quality of life (HRQoL) in a population of young adults with CF.
methodsWe administered three standardized questionnaires to 67 patients with CF aged 18-30 years; Morisky Medication Adherence Scale, Major Depression Inventory, and Cystic Fibrosis Questionnaire-Revised.
resultsThere was a response rate of 77 % and a majority of the young adults (84 %) were employed or in an education program. Most participants (74 %) reported low adherence to medications. One third (32.8 %) of the participants reported symptoms of depression. HRQoL scores were especially low on Vitality and Treatment Burden, and symptoms of depression were associated with low HRQoL scores (p < 0.01) with medium to large deficits across on all HRQoL domains (Cohen's d 0.60-1.72) except for the domain treatment burden. High depression symptom scores were associated with low adherence (r = -0.412, p < 0.001).
conclusionsDespite improved physical health, many patients with CF report poor adherence, as well as impaired mental wellbeing and HRQoL. Thus, more attention to mental health issues is needed.
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