ArticleThe Pan African medical journal2016
[Transcranial doppler in sickle cell disease (SCD) in Malagasy children].
Article in The Pan African medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- [Prevalence of sickle cell trait in blood donors at the regional blood transfusion center in the Haute Matsiatra Region, Madagascar].The Pan African medical journal · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTranscranial Doppler is an effective diagnostic tool to detect sickle cell children at risk for stroke.
methodsWe conducted a cross-sectional descriptive study of Malagasy children aged between 24 months and 15 years (group 1: 57 sickle cell diseases, group 2: 43 controls) to assess the cerebral artery velocimetry in the patient population. Transcranial doppler ultrasound with analysis of cerebral blood flow was performed in children of both groups.
resultsIn subjects with sickle cell disease, the mean velocity (MV) in the middle cerebral artery was 100.9 ± 26.8 cm/s, pulsatility index (PI) was 0.73 ± 0.20, the difference between the right and left middle cerebral artery (MCA) was 19.8 ± 21.5 cm/s, anterior cerebral artery/middle cerebral artery flow velocity ratio (ACA / MCA) was 0.7 ± 0.2. In children without sickle cell disease, MV: 80.6 ± 19.3 cm/s, IP: 0.79 ± 0.14, ACMr: 17 ± 20.1 cm/s, ACA/ACM: 0,8 ± 0,2. The velocity in children with sickle cell disease was higher than in the control group. Velocities were correlated with hemoglobin and age but not with sex and mean corpuscular volume.
conclusionCerebral Circulation Speeds are higher in children with sickle cell disease and are influenced by hemoglobin levels and age.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.