ArticleFrontiers in plant science2016
De Novo Sequencing and Analysis of Lemongrass Transcriptome Provide First Insights into the Essential Oil Biosynthesis of Aromatic Grasses.
Article in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 48 citations in OpenAlex.
- mRNA sequencing revealed transcriptional variability of terpene and eugenol synthase genes among distinct oil yielding accessions of Ocimum sanctum L.Scientific reports · 2026Article
- Divergent Roles of the Auxin Response Factors in Lemongrass (International journal of molecular sciences · 2024Article
- The Cytokinins BAP and 2-iP Modulate Different Molecular Mechanisms on Shoot Proliferation and Root Development in Lemongrass (Plants (Basel, Switzerland) · 2023Article
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- Suffer or Survive: Decoding Salt-Sensitivity of Lemongrass and Its Implication on Essential Oil Productivity.Frontiers in plant science · 2022Article
- Lemongrass Essential Oil Components with Antimicrobial and Anticancer Activities.Antioxidants (Basel, Switzerland) · 2021Review
- Revealing floral metabolite network in tuberose that underpins scent volatiles synthesis, storage and emission.Plant molecular biology · 2021Article
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- A Comprehensive Survey on the Terpene Synthase Gene Family Provides New Insight into Its Evolutionary Patterns.Genome biology and evolution · 2019Article
- Lateral transfers of large DNA fragments spread functional genes among grasses.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- De novo transcriptome sequencing and metabolite profiling analyses reveal the complex metabolic genes involved in the terpenoid biosynthesis in Blue Anise Sage (Salvia guaranitica L.).DNA research : an international journal for rapid publication of reports on genes and genomes · 2018Article
- Augmentation of crop productivity through interventions of omics technologies in India: challenges and opportunities.3 Biotech · 2018Review
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- Transcriptome analysis reveals the genetic basis underlying the biosynthesis of volatile oil, gingerols, and diarylheptanoids in ginger (Zingiber officinale Rosc.).Botanical studies · 2017Article
- Transcriptomic insight into terpenoid and carbazole alkaloid biosynthesis, and functional characterization of two terpene synthases in curry tree (Murraya koenigii).Scientific reports · 2017Article
- RNA-Seq Analysis Provides the First Insights into the Phylogenetic Relationship and Interspecific Variation betweenFrontiers in plant science · 2017Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aromatic grasses of the genus Cymbopogon (Poaceae family) represent unique group of plants that produce diverse composition of monoterpene rich essential oils, which have great value in flavor, fragrance, cosmetic, and aromatherapy industries. Despite the commercial importance of these natural aromatic oils, their biosynthesis at the molecular level remains unexplored. As the first step toward understanding the essential oil biosynthesis, we performed de novo transcriptome assembly and analysis of C. flexuosus (lemongrass) by employing Illumina sequencing. Mining of transcriptome data and subsequent phylogenetic analysis led to identification of terpene synthases, pyrophosphatases, alcohol dehydrogenases, aldo-keto reductases, carotenoid cleavage dioxygenases, alcohol acetyltransferases, and aldehyde dehydrogenases, which are potentially involved in essential oil biosynthesis. Comparative essential oil profiling and mRNA expression analysis in three Cymbopogon species (C. flexuosus, aldehyde type; C. martinii, alcohol type; and C. winterianus, intermediate type) with varying essential oil composition indicated the involvement of identified candidate genes in the formation of alcohols, aldehydes, and acetates. Molecular modeling and docking further supported the role of identified protein sequences in aroma formation in Cymbopogon. Also, simple sequence repeats were found in the transcriptome with many linked to terpene pathway genes including the genes potentially involved in aroma biosynthesis. This work provides the first insights into the essential oil biosynthesis of aromatic grasses, and the identified candidate genes and markers can be a great resource for biotechnological and molecular breeding approaches to modulate the essential oil composition.
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