ArticleJournal of applied physiology (Bethesda, Md. : 1985)2016
Improved single muscle fiber quality in the oldest-old.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 37 citations in OpenAlex.
- Circulating Interleukin-6 Is Associated with Skeletal Muscle Strength, Quality, and Functional Adaptation with Exercise Training in Mobility-Limited Older Adults.The Journal of frailty & aging · 2020Trial
- Relationship of Physical Function to Single Muscle Fiber Contractility in Older Adults: Effects of Resistance Training With and Without Caloric Restriction.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019Trial
- Marked irregular myofiber shape is a hallmark of human skeletal muscle ageing and is reversed by heavy resistance training.Journal of cachexia, sarcopenia and muscle · 2024Article
- The molecular athlete: exercise physiology from mechanisms to medals.Physiological reviews · 2023Review
- Skeletal muscle aging and sarcopenia: Perspectives from mechanical studies of single permeabilized muscle fibers.Journal of biomechanics · 2023Review
- Single muscle fibre contractile function with ageing.The Journal of physiology · 2022Review
- Single skeletal muscle fiber mechanical properties: a muscle quality biomarker of human aging.European journal of applied physiology · 2022Review
- Effects of continuous cycling training on motor unit firing rates, input excitation, and myosin heavy chain of the vastus lateralis in sedentary females.Experimental brain research · 2022Article
- Influenza Infection has Fiber Type-Specific Effects on Cellular and Molecular Skeletal Muscle Function in Aged Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- CaAmerican journal of physiology. Cell physiology · 2020Article
- Age Dependent Modification of the Metabolic Profile of the Tibialis Anterior Muscle Fibers in C57BL/6J Mice.International journal of molecular sciences · 2020Article
- Fiber typing human skeletal muscle with fluorescent immunohistochemistry.Journal of applied physiology (Bethesda, Md. : 1985) · 2019Review
- Single-muscle fiber contractile properties in lifelong aerobic exercising women.Journal of applied physiology (Bethesda, Md. : 1985) · 2019Article
- Passive force and viscoelastic properties of single fibers in human aging muscles.European journal of applied physiology · 2019Article
- The Importance of Resistance Exercise Training to Combat Neuromuscular Aging.Physiology (Bethesda, Md.) · 2019Review
- Skeletal Muscle Fiber Size and Gene Expression in the Oldest-Old With Differing Degrees of Mobility.Frontiers in physiology · 2019Article
- Impaired Muscle Efficiency but Preserved Peripheral Hemodynamics and Mitochondrial Function With Advancing Age: Evidence From Exercise in the Young, Old, and Oldest-Old.The journals of gerontology. Series A, Biological sciences and medical sciences · 2018Article
- Effects of elevated HThe Journal of physiology · 2018Article
- To hypertrophy and beyond! Myostatin and its association to intermuscular adipose tissue with exercise and aging.American journal of physiology. Regulatory, integrative and comparative physiology · 2018Article
- Mechanisms of sarcopenia: motor unit remodelling and muscle fibre type shifts with ageing.The Journal of physiology · 2018Article
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Authors and funding
13 authors at 7 institutions in 1 country.
Funding
Abstract
We examined single muscle fiber contractile function of the oldest-old (3F/2M, 89 ± 1 yr old) enrolled in The Health, Aging, and Body Composition Study (The Health ABC Study). Vastus lateralis muscle biopsies were obtained and single muscle fiber function was determined (n = 105) prior to myosin heavy chain (MHC) isoform identification with sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Cross-sectional area of MHC I muscle fibers (5,576 ± 333 μm
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.