Evidence map›Paper›PMID 27515787›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2016

Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures.

Adem Ozcelik, Nitesh Nama, Po-Hsun Huang, Murat Kaynak, Melanie R McReynolds, Wendy Hanna-Rose, Tony Jun Huang

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Review
  2. Article
  3. Lab on an end: Micromanipulation using the acoustohydrodynamic pillar array as an end effector.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. [High stability enhanced ultrasonic microfluidic structure with flexible tip coupled bubbles].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adem OzcelikDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.
Nitesh NamaDepartment of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA, 16802, USA.
Po-Hsun HuangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.
Murat KaynakDepartment of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA, 16802, USA.
Melanie R McReynoldsDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, 16802, USA.
Wendy Hanna-RoseDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, 16802, USA.
Tony Jun HuangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA. tony.huang@duke.edu.

Funding

Standing Surface Acoustic Wave Based Cell Sorters for Maintaining Cell IntegrityR01GM112048 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI HUANG, TONY JUN · 2014 to 2017
$1.1M
Validation of acoustic tweezers for single-cell analyses of purine metabolismR33EB019785 · NIBIB · PENNSYLVANIA STATE UNIVERSITY, THE · PI HUANG, TONY JUN · 2014 to 2016
$1.1M
NIBIB NIH HHS R33 EB019785NIGMS NIH HHS R01 GM112048
6 · The paper itself

Abstract

A polydimethylsiloxane microchannel featuring sidewall sharp-edge structures and bare channels, and a piezoelement transducer is attached to a thin glass slide. When an external acoustic field is applied to the microchannel, the oscillation of the sharp-edge structures and the thin glass slide generate acoustic streaming flows which in turn rotate single cells and C. elegans in-plane and out-of-plane.

Indexed as

RotationAcousticsAnimalsCaenorhabditis elegansHeLa CellsHumansNeuronsacoustofluidicsC. elegansmicrofluidicsrotational manipulations

Identifiers

PMID27515787
PMCPMC5388358

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.