Evidence map›Paper›PMID 27515388›Full record

ArticleScientific reports2016

Histological response of soda-lime glass-ceramic bactericidal rods implanted in the jaws of beagle dogs.

José S Moya, Arturo Martínez, Roberto López-Píriz, Francisco Guitián, Luis A Díaz, Leticia Esteban-Tejeda, Belén Cabal, Federico Sket, Elisa Fernández-García, Antoni P Tomsia and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

José S MoyaNanomaterials and Nanotechnology Research Center (CINN), CSIC - University of Oviedo (UO), Avda de la Vega 4-6, El Entrego 33940, San Martín del Rey Aurelio, Spain.
Arturo MartínezGalician Institute of Ceramics, University of Santiago de Compostela, Avda Maestro Mateo, 15782 Santiago de Compostela, Spain.
Roberto López-PírizNanomaterials and Nanotechnology Research Center (CINN), CSIC - University of Oviedo (UO), Avda de la Vega 4-6, El Entrego 33940, San Martín del Rey Aurelio, Spain.
Francisco GuitiánGalician Institute of Ceramics, University of Santiago de Compostela, Avda Maestro Mateo, 15782 Santiago de Compostela, Spain.
Luis A DíazNanomaterials and Nanotechnology Research Center (CINN), CSIC - University of Oviedo (UO), Avda de la Vega 4-6, El Entrego 33940, San Martín del Rey Aurelio, Spain.
Leticia Esteban-TejedaInstitute of Materials Science of Madrid (ICMM-CSIC), Cantoblanco, 28049, Madrid, Spain.
Belén CabalNanomaterials and Nanotechnology Research Center (CINN), CSIC - University of Oviedo (UO), Avda de la Vega 4-6, El Entrego 33940, San Martín del Rey Aurelio, Spain.
Federico SketIMDEA Materials Institute, C/ Eric Kandel 2, Getafe, 28906, Madrid, Spain.
Elisa Fernández-GarcíaNanomaterials and Nanotechnology Research Center (CINN), CSIC - University of Oviedo (UO), Avda de la Vega 4-6, El Entrego 33940, San Martín del Rey Aurelio, Spain.
Antoni P TomsiaMaterials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Ramón TorrecillasNanomaterials and Nanotechnology Research Center (CINN), CSIC - University of Oviedo (UO), Avda de la Vega 4-6, El Entrego 33940, San Martín del Rey Aurelio, Spain.
Nanomaterials and Nanotechnology Research Center · ESUniversidad de Oviedo · ESUniversidade de Santiago de Compostela · ESIMDEA Materials · ESInstituto de Ciencia de Materiales de Sevilla · ESLawrence Berkeley National Laboratory · US

Funding

Complex Nanocomposites for Bone RegenerationR01DE015633 · NIDCR · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI TOMSIA, ANTONI P · 2003 to 2013
$9.2M
NIDCR NIH HHS R01 DE015633
6 · The paper itself

Abstract

Bacterial and fungal infections remain a major clinical challenge. Implant infections very often require complicated revision procedures that are troublesome to patients and costly to the healthcare system. Innovative approaches to tackle infections are urgently needed. We investigated the histological response of novel free P2O5 glass-ceramic rods implanted in the jaws of beagle dogs. Due to the particular percolated morphology of this glass-ceramic, the dissolution of the rods in the animal body environment and the immature bone formation during the fourth months of implantation maintained the integrity of the glass-ceramic rod. No clinical signs of inflammation took place in any of the beagle dogs during the four months of implantation. This new glass-ceramic biomaterial with inherent bactericidal and fungicidal properties can be considered as an appealing candidate for bone tissue engineering.

Indexed as

Prostheses and ImplantsAnimalsAnti-Bacterial AgentsBiocompatible MaterialsCalcium CompoundsCeramicsDogsJawMicroscopy, Electron, ScanningOrthognathic Surgical ProceduresOsseointegrationOxidesPorositySodium HydroxideSpectrometry, X-Ray EmissionTomography, X-Ray ComputedAnti-Bacterial AgentsBiocompatible MaterialsCalcium CompoundsGlass ceramicsOxidessoda limeSodium Hydroxide

Identifiers

PMID27515388
PMCPMC4981854
OpenAlexW2516751008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.